Instituto De Oftalmología Fundación Conde De Valenciana

This trial compares two versions of a surgery called external dacryocystorhinostomy, which creates a new drainage path for a blocked tear duct. Half of the participants receive the standard surgery, while the other half receive the surgery plus a piece of amniotic membrane placed…

This trial tests whether adding insulin to autologous serum eye drops (made from a patient's own blood) improves symptoms and signs of moderate to severe dry eye in people with autoimmune conditions like Sjögren's syndrome. Researchers will compare standard serum drops against se…

This trial compares two surgical techniques for removing a pterygium, a fleshy growth on the eye's surface that can distort vision. Researchers are testing whether using a piece of the patient's own conjunctiva (the clear tissue covering the eye) or a preserved amniotic membrane …

This study tested whether cleaning the eyelids with wipes containing chlorhexidine can treat blepharitis caused by Demodex mites. 106 adults with the condition used the wipes twice daily for four weeks. Researchers measured mite counts and eyelash debris before and after treatmen…

This completed Phase 4 trial tested whether injecting 5-fluorouracil directly into raised facial scars around the eyes could make them less noticeable. Seven adults with scars from injury or cosmetic surgery received the treatment. The study used a standard scar scale to measure …

This pilot study tested whether very small doses of botulinum toxin (microbotox) injected into the skin around the eyes could reduce oiliness and shrink large pores. Thirty adults with mild to moderate fine wrinkles received one treatment. Researchers measured sebum production an…

This study tested whether injecting triamcinolone acetonide into the eyelid could help people with thyroid eye disease who have a retracted upper eyelid. Fifteen adults received a combination of two injections and were measured one month later. The goal was to see if the eyelid p…

This completed Phase 4 trial tested a duosomal chemical peel to improve skin quality around the eyes and face. Twelve adults received a customized acid peel (salicylic, mandelic, lactic, or glycolic acid) based on their skin type. Researchers measured skin improvement using both …

This completed Phase 4 trial tested whether applying exosomes (tiny particles from cells) to the face with a microneedling device can reduce signs of skin aging. Thirty men and women over 50 with wrinkles and other aging signs received three treatments, each four weeks apart. Res…

This study looked at 20 adults who wear an artificial eye to see if it causes more dry eye symptoms and damage to the tiny oil glands in the eyelids. Researchers compared the artificial eye side with the healthy eye side using special imaging and questionnaires. The goal was to u…

This study tested a digital color scale to objectively measure scarring of the eye's surface in people with recurrent pterygium, a growth that can come back after surgery. Researchers took photos of 25 patients' eyes and used software to analyze the scar tissue. The goal was to s…