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Microbotox: a new needle trick for shiny faces?

NCT ID NCT07526870

Symptom relief Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether very small doses of botulinum toxin (microbotox) injected into the skin around the eyes could reduce oiliness and shrink large pores. Thirty adults with mild to moderate fine wrinkles received one treatment. Researchers measured sebum production and patient satisfaction after six weeks. The goal was to see if this approach is safe and effective for improving skin texture without freezing muscles.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Botulinum toxin type A (Dysport®) given as tiny skin injections
What this could lead to
If it works, this could offer a simple, low-risk cosmetic option for reducing facial oiliness and large pores.
What could go wrong
This is a very small pilot study with only 30 people and no comparison group, so results may not be reliable or generalizable. The effect may be minor or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jul 2024

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 35 years * Both male and female participants * Presence of mild to moderate periocular fine wrinkles * Willingness to undergo intradermal botulinum toxin injections * Ability to provide written informed consent Exclusion Criteria: * Previous botulinum toxin treatment in the periocular area within the last 6 months * Known hypersensitivity to botulinum toxin or its components * Active skin infection or dermatologic disease in the treatment area * Neuromuscular disorders * Pregnancy or breastfeeding * Use of medications affecting neuromuscular transmission * History of eyelid or periocular surgery within the last 6 months

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Facial aging Facial wrinkles and rhytides reduction

Contacts and locations

Locations

  • ✔ Instituto de Oftalmología Fundación Conde de Valenciana IAP

    Mexico City, Mexico

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