Can different fillers turn back the clock on facial aging?
NCT ID NCT07744464
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study is looking at how well hyaluronic acid dermal fillers with different levels of crosslinking work for facial aesthetic treatment. Twenty adults seeking facial rejuvenation will receive these fillers and be followed for 90 days. Researchers will measure changes using 3D imaging, ultrasound, and satisfaction surveys, while also tracking any side effects. The goal is to see which filler characteristics offer the best balance of effectiveness, safety, and patient satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Injectable hyaluronic acid dermal fillers with different degrees of divinyl sulfone crosslinking
- What this could lead to
- If successful, this could help refine how dermal fillers are chosen for facial rejuvenation, potentially improving aesthetic outcomes and patient satisfaction.
- What could go wrong
- This is a small observational study with only 20 participants, so results may not apply broadly. Fillers carry risks like swelling, bruising, or rare complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older. Male or female participants. Seeking facial aesthetic treatment with hyaluronic acid dermal fillers. Clinical indication for treatment according to the investigator's assessment. Willing and able to provide written informed consent. Willing to comply with all scheduled visits, assessments, and follow-up procedures. Able to undergo standardized photographic documentation, three-dimensional facial imaging (Vectra® 3D), ultrasonography, and patient-reported outcome assessments. Exclusion Criteria: * Pregnancy or breastfeeding. Known hypersensitivity to hyaluronic acid or any component of the dermal filler. Active infection, inflammation, or skin disease at the intended treatment site. Previous facial aesthetic procedure that could interfere with study assessments, according to the investigator's judgment. Participation in another clinical study that could affect study outcomes. Any medical condition considered by the investigator to make participation unsafe or interfere with study evaluations. Inability or unwillingness to complete the follow-up schedule or study assessments.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Instituto Antony Barbosa
Belo Horizonte, Minas Gerais, 30493-240, Brazil
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