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Which eye surgery better restores clear vision after pterygium?

NCT ID NCT07742995

Disease control Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 18, 2026 · Updated 3 times

Summary

This trial compares two surgical techniques for removing a pterygium, a fleshy growth on the eye's surface that can distort vision. Researchers are testing whether using a piece of the patient's own conjunctiva (the clear tissue covering the eye) or a preserved amniotic membrane better restores the eye's natural shape and improves vision. Adults with a primary nasal pterygium that extends onto the cornea may participate. The study measures changes in corneal astigmatism and visual acuity over 12 months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Surgical procedure: either conjunctival autograft or amniotic membrane transplantation after pterygium removal
What this could lead to
If one technique proves better, it could become the preferred surgery for pterygium, helping more people regain clearer vision and a more regular corneal shape.
What could go wrong
This is a single trial with 78 participants, so results may not apply to everyone. As with any eye surgery, there are risks like infection, inflammation, or the pterygium returning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

78 people

The number who actually took part.

Started

Apr 2013

Finished

Mar 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with primary nasal pterygium who underwent pterygium excision with either conjunctival autograft (CAG) or amniotic membrane transplantation (AMT) at the Institute of Ophthalmology "Fundación Conde de Valenciana," Mexico City, Mexico, between April 2013 and March 2015. Eligible patients were identified from institutional clinical records according to the predefined inclusion and exclusion criteria. The surgical technique had been selected according to the treating surgeon's clinical judgment and was not assigned as part of the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Diagnosis of primary nasal pterygium in one or both eyes. * Pterygium extending at least 1 mm onto the cornea. * Underwent primary pterygium excision with either conjunctival autograft (CAG) or amniotic membrane transplantation (AMT). Exclusion Criteria: * Corneal scars. * Corneal ectatic disorders. * History of ocular trauma. * Previous ocular surgery. * Cicatrizing ocular surface disease. * Cataract or any other ocular condition that could affect visual function.

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Conditions

The condition(s) this trial relates to.

astigmatism conjunctival pterygium pterygium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Astigmatism Primary pterygium

More trials for these conditions

Other studies related to the condition(s) this trial covers.