Hackensack Meridian Health
Clinical trials sponsored by Hackensack Meridian Health, explained in plain language.
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New combo therapy shows promise for untreated CLL patients
Disease control CompletedThis study tested a treatment for people with previously untreated chronic lymphocytic leukemia (CLL). Participants received a combination of chemotherapy drugs (fludarabine and cyclophosphamide) plus the immunotherapy rituximab, along with lenalidomide, followed by lenalidomide …
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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New drug combo may boost stem cell transplant success in myeloma
Disease control CompletedThis study tested whether adding the drug bortezomib to the standard chemotherapy before a donor stem cell transplant could help people with multiple myeloma live longer without their cancer getting worse. Fifty-four adults aged 18 to 69 with a suitable donor took part. The goal …
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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Cancer drug shows promise in rare blood cancer study
Disease control CompletedThis study tested the drug carfilzomib in 7 people with Waldenström's macroglobulinemia, a rare blood cancer, after their disease returned. The goal was to see if the drug could shrink tumors and control the cancer. Carfilzomib is already approved for another blood cancer but not…
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New combo may Re-Sensitize Drug-Resistant myeloma
Disease control CompletedThis study tested whether adding a drug called vorinostat to the standard combination of lenalidomide and dexamethasone could help people with multiple myeloma whose cancer had stopped responding to lenalidomide. The trial enrolled 25 patients with relapsed or refractory myeloma.…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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Your voice may reveal early Alzheimer's: new app tested
Diagnosis CompletedThis study tested a smartphone app that analyzes voice recordings to see if it can accurately diagnose mild cognitive impairment (MCI) and Alzheimer's disease. Researchers compared the app's diagnosis to a doctor's diagnosis in 150 adults aged 50 and older. The goal was to find o…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Diagnosis
Last updated May 01, 2026 15:59 UTC
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Helping with housing and food boosts lung cancer screening rates, study finds
Knowledge-focused CompletedThis study tested whether helping people with social needs like housing, food, or transportation could increase lung cancer screening rates. About 100 adults aged 50-80 who were current or former heavy smokers took part. One group received standard education about lung screening,…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Gut bugs could boost breast cancer chemo
Knowledge-focused CompletedThis study looked at 49 women with triple negative breast cancer to see if the bacteria in their gut and tumors affected how well chemotherapy worked. Researchers collected samples before and during treatment to find links between certain bacteria and a complete response. The goa…
Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:04 UTC