Hackensack Meridian Health
Clinical trials sponsored by Hackensack Meridian Health, explained in plain language.
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Double-Dose transplant strategy for myeloma shows promise
Disease control CompletedThis completed phase 3 trial tested a two-step treatment for multiple myeloma. Patients received high-dose melphalan chemotherapy followed by a stem cell transplant, then a second round with melphalan plus bortezomib (Velcade) and another transplant. The goal was to see if this t…
Phase: PHASE3 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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Can a drug combo overcome resistance in multiple myeloma?
Disease control CompletedThis study tested whether adding a drug called vorinostat to the standard combination of lenalidomide and dexamethasone could help patients whose multiple myeloma had stopped responding to lenalidomide. The trial enrolled 25 adults with relapsed or refractory multiple myeloma. Th…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 22, 2026 12:07 UTC
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New drug cocktail may boost stem cell transplant success in blood cancer
Disease control CompletedThis study tested whether adding the drug bortezomib to the standard chemotherapy before a donor stem cell transplant could help people with multiple myeloma live longer without their cancer getting worse. Fifty-four adults received the new drug combo. The main goal was to see if…
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 22, 2026 12:04 UTC
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Stem cell 'Educator' shows promise in early diabetes trial
Disease control CompletedThis early study tested a new treatment called Stem Cell Educator therapy in 13 adults with type 1 diabetes. The goal was to see if the treatment is safe and possible to do. Researchers used a device to 'educate' the patient's own immune cells outside the body and then return the…
Phase: PHASE1 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 17, 2026 12:07 UTC
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Cancer drug shows promise in rare blood cancer
Disease control CompletedThis study tested the drug carfilzomib in 7 people with Waldenström's macroglobulinemia, a rare blood cancer, that had returned after previous treatment. The goal was to see if the drug could shrink tumors and control the cancer. Carfilzomib works by blocking a protein that helps…
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 17, 2026 12:04 UTC
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New drug cocktail shows promise for Tough-to-Treat myeloma
Disease control CompletedThis study tested adding thalidomide to two other chemotherapy drugs (bortezomib and melphalan) before a stem cell transplant in 29 people with advanced multiple myeloma who had already tried a similar transplant. The goal was to find the safest dose of thalidomide and see if the…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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New cocktail may boost transplant success in blood cancer
Disease control CompletedThis study tested adding lenalidomide to a standard chemotherapy regimen (RICE) for people with diffuse large B-cell lymphoma that had come back after initial treatment. The goal was to see if the combination could shrink tumors more effectively, allowing more patients to proceed…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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New hope for CLL patients: drug combo shows promise in early trial
Disease control CompletedThis study tested a treatment for people with previously untreated chronic lymphocytic leukemia (CLL). Participants received a combination of chemotherapy drugs (fludarabine, cyclophosphamide, rituximab) plus lenalidomide, followed by lenalidomide alone to keep the disease under …
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 03, 2026 12:06 UTC
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Could a simple pad replace invasive biopsies for uterine cancer?
Diagnosis CompletedThis study tested a special pad worn for 4-6 hours to collect cells shed from the uterus. Researchers wanted to see if the pad could gather enough cells to tell the difference between normal tissue, precancerous changes, and cancer. 80 women scheduled for surgery wore the pad, an…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Diagnosis
Last updated Jun 23, 2026 11:56 UTC
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Your voice may reveal Alzheimer's: new app tested for diagnosis
Diagnosis CompletedThis study tested a smartphone app that analyzes voice recordings to see if it can accurately diagnose mild cognitive impairment (MCI) and Alzheimer's disease. Researchers compared the app's diagnosis to a doctor's diagnosis in 150 adults aged 50 and older. The goal was to see if…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Diagnosis
Last updated Jun 11, 2026 12:11 UTC
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Helping with housing and food may get more people screened for lung cancer
Knowledge-focused CompletedThis study tested whether helping people with social needs like housing, food, or transportation could increase lung cancer screening rates. 101 adults aged 50-80 who smoked heavily were split into two groups: one got standard education about lung screening, and the other also go…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Jun 23, 2026 12:00 UTC
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Gut bacteria linked to chemo success in aggressive breast cancer
Knowledge-focused CompletedThis study looked at whether the types of bacteria in the gut and inside tumors affect how well chemotherapy works in triple negative breast cancer. Researchers followed 49 patients receiving standard chemotherapy before surgery. They collected samples to see if certain bacteria …
Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:57 UTC
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Facebook ads boost lung cancer screening awareness in smokers
Knowledge-focused CompletedThis study tested whether Facebook ads and a tailored online tool called LungTalk could help people at high risk for lung cancer learn more about screening. Over 500 current or former heavy smokers participated. The goal was to see if social media can effectively reach and educat…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC