Hackensack Meridian Health

This phase 2 study tests the drug selinexor combined with one of three other cancer drugs (carfilzomib, daratumumab, or pomalidomide) in 96 adults with multiple myeloma whose disease has worsened despite current treatment. Participants continue on the combination until the cancer…

This study aimed to test whether giving the antibiotic ceftriaxone every 5 days for about 6 weeks could kill the bacteria causing persistent Lyme disease symptoms. It planned to enroll people aged 18-75 with Post-Treatment Lyme Disease Syndrome. However, the trial was withdrawn b…

This study tests a combination of four drugs (carfilzomib, lenalidomide, vorinostat, and dexamethasone) in people whose multiple myeloma has returned or stopped responding to prior treatments. The goal is to find a safe dose and see how well the drugs control the cancer. 17 parti…

This early-phase study tests a combination of three drugs (ibrutinib, lenalidomide, and rituximab) in people with mantle cell lymphoma that has returned or not responded to prior treatment. The main goal is to find the safest dose of this combination by monitoring side effects. U…

This study tests whether placing a cryopreserved umbilical cord allograft around nerves during robotic prostatectomy helps men regain erectile function and bladder control sooner. About 100 men with prostate cancer will be randomly assigned to receive either standard surgery or s…

This pilot study looks at whether full-term newborns with mild breathing problems can safely go without a breathing machine called CPAP. About 22 babies born by scheduled C-section will be watched closely for 20 minutes after birth. The goal is to see if they can breathe on their…

This study explores how to add a mental health program called Mothers and Babies into existing home visiting services for pregnant people and new parents in Iowa and Indiana. Researchers will work with 1,750 home visitors and program recipients to see how well the program is adop…

This study aimed to see if a test measuring blood flow in tiny leg vessels could predict whether a leg can be saved in people with severe peripheral artery disease. It was designed for adults with chronic critical limb ischemia who had a procedure to reopen blocked arteries. Howe…