Gustave Roussy, Cancer Campus, Grand Paris

This early-phase study tested the drug RAD001 (everolimus) combined with radiation therapy in 26 people with advanced non-small cell lung cancer that could not be removed by surgery. The main goal was to find the safest dose and identify side effects. Participants took RAD001 wee…

This study looked at 150 colorectal cancer patients who had a high chance of cancer spreading to the lining of the belly. After standard chemotherapy, half received only follow-up checks, while the other half had exploratory surgery plus heated chemotherapy (HIPEC) directly into …

This study tested whether adding the immunotherapy drug atezolizumab to standard chemoradiotherapy helps people with locally advanced cervical cancer. About 189 participants received either the combination or standard treatment alone. The goal was to see if the drug delays cancer…

This study tested a chemotherapy drug called cabazitaxel in 34 men with advanced testicular cancer that had not responded to at least two prior treatments. The goal was to see if the drug could shrink tumors or stop them from growing. Cabazitaxel is a newer type of taxane that ma…

This study tested whether adding 6 doses of the drug rituximab to standard chemotherapy helps children and teens with advanced B-cell lymphoma or leukemia live longer without the cancer coming back. About 482 high-risk patients aged 6 months to 18 years took part. The goal was to…

This study tested a treatment called DA-EPOCH-Rituximab in 47 children and teens with a rare type of lymphoma (PMLBL). The goal was to see if this combination of chemotherapy and a targeted antibody could improve how long patients stay cancer-free. Participants received the drug …

This early-phase study tested a combination of two drugs, temsirolimus and cetuximab, in 45 adults with advanced or metastatic solid tumors that no longer responded to standard treatments. The goal was to see if blocking two cancer growth pathways at once could be safe and more e…

This study tested whether adding targeted drugs (trametinib and dabrafenib) to radioactive iodine can help shrink tumors in people with advanced thyroid cancer that has stopped responding to standard radioactive iodine treatment. The trial included 40 adults with specific gene mu…

This early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and nintedanib (an anti-angiogenesis drug)—in 196 adults with advanced solid tumors that had worsened after standard treatment. The main goal was to find the safest dose of nintedanib when g…

This study tested a new, optimized version of angiomammography, a special breast X-ray, against the standard technique. About 100 women aged 40 to 70 who needed this exam took part. The goal was to see if the new method produces clearer images with fewer artifacts, which could he…

This study tested two improvements for wheelchair transport in a cancer hospital: a new seat and a system to attach IV poles directly to the wheelchair. The goal was to see if these changes could shorten travel time and make rides more comfortable for 154 adult patients. The hosp…

This study tested whether a personalized phone-based program that coaches overweight breast cancer patients on diet and exercise can reduce fatigue better than standard health education. The program used motivational coaching to help participants lose weight and adopt healthier h…

This study asked men with advanced prostate cancer which of two standard chemotherapies they preferred based on side effects. 195 patients tried both drugs in sequence and then stated their preference. The goal was to understand which treatment is better tolerated, helping doctor…

This study tested an online program to help cancer patients with insomnia. 348 adults with cancer who had trouble sleeping used a step-by-step website with videos and tools. The goal was to see who benefits from extra help from a professional and what kind of support they need.

This study looked at whether a new robotic system (da Vinci Xi) can be used for surgery on head and neck tumors. It included 100 adults with different types and stages of head and neck cancer. The main goal was to see how often the robotic surgery could be completed successfully.

This study followed 100 adults with a rare, non-cancerous tumor called peripheral primitive fibromatosis. Instead of treating everyone right away, doctors simply monitored the tumors to see how they changed over three years. The goal was to find clues that predict which tumors wi…

This study looked at long-term brain health in 92 adults who had chemotherapy for bone tumors (osteosarcoma or Ewing sarcoma) as children or teens. Researchers measured thinking, memory, and concentration problems using a questionnaire. The goal was to understand which factors ar…

This study looked at tumors from 791 children whose cancers had come back or stopped responding to standard treatments. Researchers used advanced genetic testing to find specific changes in each child's tumor that could be targeted by existing drugs. The goal was to see how many …

This study looked at 141 cancer patients starting targeted therapies to track and describe any skin problems that occurred. The goal was to better understand why these side effects happen and how they appear. No new treatment was tested; instead, researchers collected data throug…