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New combo therapy shows promise against rare childhood lymphoma

NCT ID NCT01516567

First seen Feb 13, 2026 · Last updated May 25, 2026 · Updated 20 times

Summary

This study tested a treatment called DA-EPOCH-Rituximab in 47 children and teens with a rare type of lymphoma (PMLBL). The goal was to see if this combination of chemotherapy and a targeted antibody could improve how long patients stay cancer-free. Participants received the drug regimen, and researchers tracked survival, side effects, and long-term health. The trial is complete, and results help guide future treatment decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • 2nd Dept. of Pediatrics Semmelweis Univ.

    Budapest, 1094, Hungary

  • Associazione Italiana di Ematologia ed Oncologia Pediatrica

    Padova, 35128, Italy

  • Children Oncology Group Operations centres

    Monrovia, Canada

  • Emma Children's Hospital

    Amsterdam, 1105 AZ, Netherlands

  • Gustave Roussy

    Villejuif, 94805, France

  • Rectorat of Medical University

    Wroclaw, Poland

  • Sociedad Española de Hematología y Oncología Pediátricas

    Valencia, 46010, Spain

  • University Hospitals Leuven

    Leuven, 3000, Belgium

  • University of Birmingham

    Birmingham, United Kingdom

Conditions

Explore the condition pages connected to this study.