Centre Hospitalier Universitaire Dijon

This trial tested a drug called taselisib for people with a rare condition that causes parts of the body to grow too much. The study included 19 people aged 16 to 65 with a specific gene mutation. The goal was to see if the drug is safe and can shrink overgrown tissue, but the st…

This study looked at whether liraglutide, a diabetes medication, could reduce fat buildup in the liver and improve cholesterol levels in people with type 2 diabetes. About 127 participants were planned, but the study was terminated early. The goal was to measure changes in liver …

This study looked at 500 adults in intensive care with septic shock and severe kidney failure. It compared starting dialysis early (within 12 hours) versus waiting 48-60 hours to see if timing affected survival at 90 days. The trial was terminated early, so results are limited.

This study tested a 6-month dental health education program for people with schizophrenia. The goal was to see if the program could improve oral hygiene and quality of life compared to standard care. The study was terminated early, so results are limited.

This study tested whether a drug called levosimendan could help people with severe heart failure successfully come off a heart-lung machine (ECLS). The trial planned to include 82 adults, but was stopped early. The goal was to see if the drug reduced the chance of needing to stay…

This study tested whether a sedative called dexmedetomidine could help restore blood pressure response in adults with severe septic shock who were not responding to standard treatments. The trial was stopped early, but it aimed to see if the drug could improve how the body reacts…

This study tested whether giving a single high dose of steroids just before colorectal surgery could lower the risk of serious complications like infections. It involved 78 adults having planned colorectal surgery for various conditions. The study was stopped early, so the result…

This study looked at whether a mindfulness-based stress reduction program could improve the mental and physical health of people caring for someone with a severe psychiatric disorder (like schizophrenia or bipolar disorder). Researchers planned to measure stress levels and signs …

This study tested whether a device called NIRS, which uses light to measure oxygen in tissues, can better predict wound healing and blood flow in people who had a leg amputation due to poor circulation. Researchers compared NIRS to the standard method (TcPO2) in 62 patients. The …

This study aimed to understand why some people taking the cancer drug ibrutinib develop heart problems like atrial fibrillation (irregular heartbeat) and high blood pressure. Researchers planned to follow 8 patients with blood cancers, using heart tests and blood markers to find …

This study aimed to confirm if a simple score can predict good vision recovery one year after combined cataract and eye membrane surgery. Researchers looked at factors like age, symptom duration, and initial vision in 164 adults aged 40 and older. The goal was to give surgeons a …

This study looked at whether a special eye scan (OCT-A) can predict how well the remaining kidney will work one year after kidney removal for cancer. Researchers enrolled 30 adults scheduled for total nephrectomy and checked their retinal blood vessels before surgery. The goal wa…

This study looked at how taste, food cravings, and eating habits differ between people with type 2 diabetes and healthy individuals. It involved 48 participants, including those starting a diabetes medication called Liraglutide, other diabetic patients not on that drug, and healt…

This study looked at 57 adults with type 1 or type 2 diabetes to see if their behavior type (proactive/impatient or calm/slow) is linked to genetic markers of inflammation and stress. Participants answered questionnaires, met with a psychologist, and gave one blood sample. The go…

This study looked at whether tiny particles called exosomes, released by tumor cells into the blood, can serve as early warning signs for colorectal cancer progression. Researchers analyzed blood samples from 172 patients to see if the number, size, and contents of these particle…

This study looked at how mechanical ventilation (breathing machines) affects the energy centers (mitochondria) of immune cells in patients with severe lung infections. Researchers aimed to understand why some patients get worse despite treatment. The study was stopped early and i…