Centre Hospitalier Universitaire Dijon

This study tests whether giving a high dose of corticosteroids just before and after surgery for digestive cancers can reduce major complications and improve long-term outcomes. The trial involves 1,200 adults undergoing planned surgery for digestive cancers. The goal is to lower…

This study looks at 120 adults with giant cell arteritis (a type of blood vessel inflammation) who are stable on tocilizumab. It compares stopping the drug suddenly versus tapering it slowly over time. The goal is to see which approach better prevents the disease from flaring up …

This study compares two drugs, methotrexate and tocilizumab, for treating giant cell arteritis, a condition that causes inflammation of large arteries. The goal is to see if the less expensive methotrexate works as well as tocilizumab at preventing relapses while reducing the nee…

This study compares two drugs, vasopressin and noradrenaline, used to maintain blood pressure during heart surgery. The goal is to see if vasopressin reduces the number of patients who develop acute kidney failure or die after surgery. About 840 adults scheduled for heart surgery…