Centre Hospitalier Régional D'orléans

This study tested whether removing feeding tubes immediately after patients in intensive care have their breathing tubes removed helps them start eating by mouth sooner. Researchers compared this early removal approach against standard care in 112 ICU patients. The goal was to se…

This small, completed pilot study compared two ways to give oxygen to people hospitalized with a sudden worsening of their chronic lung disease (COPD). It tested a newer method called High-Flow Nasal Oxygen against the standard treatment, Noninvasive Ventilation, over the first 2…

This study tested whether a near-infrared light device helps nurses insert IV lines on the first try in intensive care patients. Critically ill patients often have swollen arms, making it hard to see or feel veins for IV access. Researchers compared the light device, which makes …

This study tested whether shiatsu, a form of Japanese massage, could help reduce the severe fatigue often experienced by people with axial spondyloarthritis, a chronic inflammatory arthritis. Seventy-two adult patients received three sessions of real shiatsu and three sessions of…

This study aimed to understand how well the Pfizer COVID-19 vaccine works in adults with weakened immune systems compared to healthy adults. Researchers measured antibody levels and their ability to fight the virus in 196 participants, including people with conditions like kidney…

This study followed 187 people who had COVID-19 to measure their antibody levels for two years. Researchers wanted to understand how long natural immunity lasts and whether antibodies remain effective against the virus over time. They also examined how vaccination affects antibod…

This study aimed to find a new biological marker (biomarker) in the blood to help monitor multiple sclerosis (MS). Researchers compared blood samples from 100 healthy people and people with stable MS who were on different treatments. They measured the levels of a specific seroton…

This study aimed to understand why inflammatory bowel diseases (IBD) like Crohn's and colitis are often more severe in children. Researchers tested the idea that DNA leaking from cells might trigger and worsen gut inflammation through a specific biological pathway. They analyzed …

This study tested whether advanced imaging techniques could predict which patients with knee osteoarthritis would experience worsening joint damage over three years. Researchers followed 167 people with painful knee arthritis, using special X-rays and MRI scans to analyze bone te…

This study aimed to improve a portable brain scanning technique (fNIRS) by finding the minimum number of repeated tasks needed to get a clear brain activity signal. Researchers measured brain activity in 29 healthy, right-handed volunteers while they performed a simple hand movem…

This study aimed to understand how safe it is to move critically ill patients within a hospital while they are receiving oxygen through a special portable high-flow device. Researchers observed 175 adult patients in intensive care who needed to be moved for tests or between depar…

This study looked at whether regular check-in interviews with a hospital pharmacist could help people with lung cancer better manage their medications and side effects. Researchers followed 60 patients receiving chemotherapy, immunotherapy, or targeted pills for 6 months. The mai…