Centre Hospitalier Régional D'orléans

This study compared high-flow nasal oxygen (HFNO) to standard noninvasive ventilation for people having a moderate COPD flare-up. 51 adults with COPD and specific blood gas levels took part. The goal was to see if HFNO could improve blood acidity and oxygen levels over 24 hours, …

This study tested whether shiatsu, a Japanese finger-pressure therapy, can reduce fatigue in people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine). 72 adults aged 18 to 70 took part. Researchers measured fatigue using a standard questionnaire …

This study followed 187 people who had COVID-19 to measure their antibody levels over 24 months. Researchers wanted to see how long antibodies stay in the body and whether they continue to work against the virus. They also looked at how the severity of the initial infection and v…

This study looked at 175 critically ill patients who needed high-flow nasal oxygen and were moved within the hospital for tests or to another unit. The goal was to see how often serious problems, like needing a breathing tube or very low oxygen levels, happened during these moves…

This study looked at how well the Pfizer COVID-19 vaccine triggered an immune response in 196 adults with weakened immune systems (like kidney transplant patients or those with cancer) compared to healthy adults. Researchers measured antibody levels in the blood and nose to see i…

This study looked at two different ways to give oxygen to healthy volunteers before anesthesia: one using a mask and a machine that helps breathing, and the other adding high-flow oxygen through the nose. The goal was to see which method raises oxygen levels faster and higher. Th…

This study tested whether having a hospital pharmacist interview lung cancer patients about their medications could reduce unplanned doctor visits or hospital stays. Sixty adults on chemotherapy, immunotherapy, or oral targeted therapy took part. Researchers tracked how many unsc…

This study looked at brain activity in 29 healthy, right-handed adults while they either moved their right hand or felt a vibration that made it seem like their hand was moving. The goal was to find out the fewest number of repetitions needed to see clear brain responses. The res…

This study looked at whether a serotonin receptor called 5-HT7 could be used as a biomarker for multiple sclerosis (MS). Researchers measured how much of this receptor was on different blood cells from 100 people, including healthy volunteers and MS patients on stable treatment. …

This study tested whether special X-ray and MRI scans of the bone beneath the knee joint can predict if osteoarthritis will get worse over 3 years. Researchers followed 167 people with knee arthritis, using imaging and bone texture analysis to track changes. The goal is to better…

This study tested whether a near-infrared light device helps nurses start an IV on the first try in ICU patients with swollen arms. About 380 critically ill adults took part. The device shines light to show veins under the skin, which may make IV placement easier and reduce patie…

This study tested if taking out the feeding tube right after the breathing tube is removed helps ICU patients start eating by mouth sooner. 112 adults who had a breathing tube for more than 48 hours took part. The goal was to see if this simple step reduces swallowing problems an…

This study looked at 40 children aged 6 to 17 with inflammatory bowel disease (IBD) to understand how DNA that escapes from cells might worsen inflammation. Researchers analyzed blood, stool, and gut tissue samples to study a specific pathway called cGAS-STING. The goal was to id…