Case Western Reserve University
Clinical trials sponsored by Case Western Reserve University, explained in plain language.
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Grape powder shows promise for Crohn's gut health
Disease control CompletedThis pilot study tested whether taking grape powder daily could improve gut health in adults with Crohn's disease, a type of inflammatory bowel disease. Twenty-one participants in remission took freeze-dried grape powder for a period. Researchers measured changes in gut bacteria …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated May 26, 2026 06:01 UTC
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Shorter seizure prevention after childbirth may be just as safe
Disease control CompletedThis study looked at whether giving magnesium sulfate for 12 hours instead of the usual 24 hours after delivery could safely prevent seizures in women with mild preeclampsia. 200 women at term were randomly assigned to either the shorter or longer treatment. The goal was to see i…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New program boosts medication adherence in bipolar youth
Disease control CompletedThis study tested a customized program to help 36 teens and young adults with bipolar disorder take their medication as prescribed. Many young people with bipolar disorder struggle with taking their meds, which can lead to relapse and higher suicide risk. The program aimed to imp…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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New program cuts stroke risk in African-American men
Disease control CompletedThis study tested a 6-month program called TEAM to help African-American men who had a stroke or mini-stroke lower their risk of another one. 160 men took part, with half getting the program and half on a waitlist. The program focused on managing blood pressure and cholesterol th…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Vaccines at the delivery room: a new way to reach men?
Prevention CompletedThis study tested whether offering vaccines and health education to men at a birthing center helps them get more preventive care. 176 male partners of women giving birth were split into three groups: one got a vaccine offer, another got an info flyer plus the offer, and a third g…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Prevention
Last updated May 20, 2026 11:54 UTC
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New painkiller may reduce need for opioids after wisdom tooth surgery
Symptom relief CompletedThis study tested whether a long-lasting painkiller (Exparel) works better than a standard one (bupivacaine) for pain after removing all four wisdom teeth. 82 adults took part, and they reported their pain and any side effects for four days after surgery. The goal was to see if E…
Phase: PHASE4 • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated May 26, 2026 06:08 UTC
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Needles vs. pain: ER acupuncture study shows promise
Symptom relief CompletedThis study tested whether acupuncture can help manage acute pain in the emergency department. Researchers enrolled 290 adults with moderate to severe pain from injuries like back or abdominal pain. Participants were randomly assigned to receive either acupuncture or usual care, a…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Exercise and therapy show promise for opioid addiction pain relief
Symptom relief CompletedThis pilot study tested whether adding exercise and pain-focused therapy to residential drug treatment is practical for adults with opioid use disorder and chronic pain. 63 participants were enrolled to see if they would stick with the program. The goal was to explore if this app…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Massive gene hunt aims to uncover roots of high blood pressure
Knowledge-focused CompletedThis study searched for genetic differences that make some people more likely to develop high blood pressure. Researchers analyzed data from over 8,600 African American and Mexican American participants. The goal was to better understand the genetic causes of this common conditio…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 26, 2026 06:08 UTC
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Diabetes in donors may cloud corneal transplant outcomes
Knowledge-focused CompletedThis study looked at whether a cornea from a donor with diabetes is more likely to fail after a transplant called DMEK. Over 1,000 people received a cornea from either a donor with or without diabetes. The goal was to see if diabetes in the donor affects how well the transplant w…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 26, 2026 06:08 UTC
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Can a ring and an app reveal your sleep secrets?
Knowledge-focused CompletedThis study looked at how well smartphone apps and a special ring can measure sleep quality in adults getting orthodontic treatment. 52 people from a dental school took part. The goal was to see if these tools could help detect sleep problems like snoring or sleep apnea, not to tr…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 26, 2026 06:01 UTC
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Study reveals key factors in hypertension Self-Care for african americans
Knowledge-focused CompletedThis study looked at 125 African American adults with high blood pressure to understand how personal strengths and self-care habits influence their health. Researchers measured blood pressure and quality of life over six months. The goal was to find new ways to help people manage…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 26, 2026 05:51 UTC
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3D heart models boost med student learning in new trial
Knowledge-focused CompletedThis study tested whether 3D-printed heart models or augmented reality help first-year medical students understand congenital heart disease better than traditional slide lectures. 26 students took a test before and after learning with one of three methods. The goal was to see if …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 26, 2026 05:48 UTC
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Wearable sensors could predict stroke recovery
Knowledge-focused CompletedThis study tested a wearable sensor system to measure arm movement in 30 people who recently had a stroke. The goal was to see if the sensors could help predict how well arm function would recover. Researchers used motion data to build a model that estimates recovery, which may l…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Navigators may help kidney patients overcome transplant barriers
Knowledge-focused CompletedThis study tested whether trained transplant navigators could help kidney failure patients complete the steps needed to get a kidney transplant. About 167 adults on dialysis took part, with some receiving navigator support and others usual care. The goal was to see if personalize…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC
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Texting program aims to boost breastfeeding rates among black moms
Knowledge-focused CompletedThis study tested whether a special texting program (TEAM2BF) designed for African-American/Black expectant mothers helps them breastfeed longer compared to a general health texting program. About 80 mothers and their babies took part. The goal was to see if the texts were helpfu…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Sleep study seeks to boost blood sugar control in young diabetics
Knowledge-focused CompletedThis study looked at whether improving sleep can help young adults (ages 18-26) with type 1 diabetes manage their blood sugar better. 39 participants either received coaching to sleep longer and more regularly or just standard diabetes education. The goal was to see if better sle…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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Can learning to cook with what you have ease stress and cut waste?
Knowledge-focused CompletedThis study aimed to find the best ways to teach cooking and food skills to adults. Researchers tested a new type of cooking class that focuses on using ingredients you already have, reducing food waste, and proper food storage. They wanted to see if these classes could help lower…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Apr 13, 2026 20:23 UTC