Boston Children's Hospital

This study tested whether adding an existing, non-hormonal drug called cabergoline to standard hormonal therapy could better control the chronic pain of endometriosis. It involved 129 adolescent and adult women with surgically-confirmed endometriosis who were already on hormonal …

This study tested if adding a drug called abatacept to the standard two-drug regimen could better prevent severe Graft vs Host Disease (GvHD) in patients receiving a stem cell transplant from an unrelated donor. GvHD is a dangerous condition where the donor's immune cells attack …

This study tested whether a special digital tool, designed like a friendly interactive character, could help reduce anxiety in children and their parents before surgery. Researchers compared this digital tool to the standard educational materials hospitals usually provide. They m…

This study aimed to find out which of two commonly used numbing medicines works better for patients recovering from jaw surgery. Researchers compared lidocaine, which works quickly but wears off faster, to bupivacaine, which takes longer to start but lasts much longer. They measu…

This study aimed to understand why people with Fibrous Dysplasia, a rare bone disorder, often experience severe pain that doesn't match the visible damage in their bones. Researchers enrolled 37 adolescents and adults to compare brain activity, mental health, and blood markers be…

This study aimed to understand how the brain responds to pain while a patient is under general anesthesia. Researchers used a special light-based scanner on the heads of 44 young patients undergoing heart procedures to measure blood flow changes in the brain during painful moment…

This study aimed to understand why keeping weight off is so hard. After losing weight, 234 adults followed one of three diets with different amounts of carbs and fat, but the same protein. Researchers carefully measured how many calories their bodies burned and other health marke…

This study aimed to understand how folic acid helps prevent spina bifida, a serious birth defect. Researchers asked 69 women who had a previous pregnancy affected by spina bifida to take folic acid supplements for three months. They measured changes in their blood to see how foli…