Barts & The London Nhs Trust

This study aims to improve a common heart procedure called catheter ablation for people with persistent atrial fibrillation (AF), a condition where the heart beats irregularly. Researchers will create detailed 3D maps of the heart's electrical activity and scar tissue during the …

This study is testing a new way to place and program a spinal cord stimulator for people with chronic back pain. Doctors will use real-time measurements of nerve activity during surgery to help position the device more precisely. The goal is to see if this method leads to better …

This study compares two common treatments for persistent atrial fibrillation (AF), an irregular heart rhythm. Researchers want to see if catheter ablation (a procedure that scars heart tissue to block faulty electrical signals) works better than electrical cardioversion (a contro…

This study is testing whether using a patient's own bone marrow stem cells can help people with severe, untreatable chest pain (refractory angina). About 110 participants will be randomly assigned to receive either the real stem cell treatment or a 'sham' placebo procedure, and n…

This study aims to understand how muscle wasting in the mouth and throat affects swallowing in critically ill adults in intensive care. Researchers will measure muscle size and swallowing ability in 160 ICU patients and compare them to less ill hospital patients. The goal is to f…

This study aims to understand why patients with cardiogenic shock (a severe form of heart failure) respond differently to treatments and have varying outcomes. Researchers will collect blood samples from 300 patients across Europe to analyze genetic patterns and immune system res…

This study aims to understand why some patients develop severe muscle weakness after surviving a life-threatening heart or lung failure that required advanced life support (ECMO) in the ICU. Researchers will observe 100 adult patients to identify what factors affect their physica…

This study aims to collect CT scan data from patients before and after they receive a TAVI procedure to replace a narrowed heart valve. Researchers want to use this scan data, along with routine heart measurements, to train a computer program to predict how well the new valve wil…

This study aims to understand how a patient's nutritional status and body composition affect their treatment outcomes for Crohn's disease and ulcerative colitis. Researchers will observe 300 patients starting new medications or having surgery, measuring things like muscle mass an…

This study aims to find out if asking patients more often about their quality of life gives a better picture of the benefits of a heart procedure called catheter ablation. It will compare this procedure to standard medication in 70 adults who have a defibrillator and a dangerous …