Barts & The London Nhs Trust

This study tested a steroid called triamcinolone in 55 men with castration resistant prostate cancer, a type that stops responding to standard hormone therapy. The goal was to see if a monthly injection could keep the cancer from growing longer than current steroid treatments, wh…

This study tested whether adding a drug called paricalcitol (similar to vitamin D) to standard chemotherapy could help people with advanced pancreatic cancer that had stopped responding to treatment. 27 adults with metastatic pancreatic cancer took part. The goal was to see if th…

This study tested a device called Reactiv8, implanted in the lower back to stimulate muscles and ease chronic low back pain. Twenty adults with long-lasting pain took part. Researchers measured changes in pain, disability, sleep, and brain activity to see if the implant helps imp…

This study aimed to create a new questionnaire that measures how atrial fibrillation (AF) affects a person's quality of life. Researchers worked with 206 people who have AF to develop and test this scale. The goal was to give doctors a better way to understand the real-world impa…

This study tested whether a daily nutritional supplement could help people recover after an ischemic stroke. Researchers gave the supplement to some patients and standard care to others. The main goal was to see if a larger study is possible, not to prove the supplement works. 24…

This study looked at how heart surgery impacts the mental health, well-being, and quality of life of adults with Marfan Syndrome, a genetic condition that weakens the body's connective tissues. Researchers asked 28 participants to fill out questionnaires about their mood, fatigue…

This study tested two methods—CoolStick and ethyl chloride spray—for checking how well anesthesia blocks sensation before a C-section. Sixty-four pregnant women having planned C-sections took part. The goal was to see which tool works better for measuring numbness, not to provide…

This completed study looked at how occipital nerve stimulation (ONS) changes pain processing in people with chronic migraine or cluster headache. Six participants had pain perception measured before and after ONS using sensory tests and questionnaires. The goal was to understand …

This small pilot study looked at 5 people with hypertrophic cardiomyopathy (thick heart muscle) who needed an implantable defibrillator to prevent dangerous heart rhythms. The goal was to see if it's possible to run a larger study comparing two types of defibrillators: one placed…