Astrazeneca

This study tests a new combination of two drugs (camizestrant and atirmociclib) in 24 people with a specific type of advanced breast cancer (ER-positive, HER2-negative) that has worsened after previous treatment. The main goal is to check safety and how the body processes the dru…

This study tracks 210 people with severe asthma in South Korea who are prescribed Tezepelumab (Tezspire). Researchers will watch for side effects and check if the drug helps control asthma over 24 weeks. The goal is to see how well the drug works in real-world use, not to cure as…

This study tests a drug called tezepelumab in 230 Chinese adults with chronic sinusitis and nasal polyps. The goal is to see if it reduces polyp size and improves nasal congestion over 24 weeks. Participants receive the drug as an injection, and doctors measure changes using nasa…

This study tests a new drug called surovatamig in people with a type of leukemia (CLL/SLL) that has a genetic marker making it harder to treat. The goal is to see if taking this drug after initial treatment helps keep the cancer from coming back longer than just watching and wait…

This study offers continued access to benralizumab (Fasenra) for people with asthma, eosinophilic granulomatosis with polyangiitis (EGPA), or hypereosinophilic syndrome (HES) who completed a previous benralizumab study and are still benefiting. About 230 participants will receive…

This study is for people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) whose cancer has spread to distant parts of the body after they finished a targeted therapy called osimertinib. The study will test whether giving osimertinib together with chemo…

This study will track 600 Korean adults with COPD who are starting the medication Breztri. Researchers want to see how safe the drug is in everyday use and whether it helps improve breathing. Participants will be followed for up to 24 weeks to record any side effects and measure …

This study tests two experimental drugs (AZD9574 and AZD2265) in people with metastatic prostate cancer that has spread. The goal is to check safety and see if the combination can shrink tumors or lower PSA levels. About 152 participants will join this early-phase trial at multip…

This study tests a combination of two targeted drugs (acalabrutinib and venetoclax) for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose cancer has returned after previous treatment. The goal is to see if this short-term therapy can control…

This study will follow about 80 Polish patients with atypical hemolytic uremic syndrome (aHUS) who are receiving ravulizumab as part of routine care. Researchers will collect data from medical records and regular check-ups to see how well the treatment controls the disease. The g…

This study aims to see if a portable device that measures lung function can accurately diagnose asthma. Researchers will compare this new method to the standard breathing tests currently used. The study will involve 500 adults in China who have asthma-like symptoms such as wheezi…

This study aims to see if training doctors on a standardized process helps them identify ATTR amyloidosis earlier in people at high risk. About 4,000 adults aged 60 and older with heart failure will be enrolled across 50 sites in China. Doctors will receive special training on di…

This study tests whether a dexamethasone mouthwash can prevent or reduce painful mouth sores caused by the cancer drug datopotamab deruxtecan (Dato-DXd). About 100 adults with advanced breast or lung cancer will use the mouthwash four times a day for the first 12 weeks of treatme…

This study looks at how the lupus medication Saphnelo (anifrolumab) is being used in women aged 15 to 50 who could become pregnant. The goal is to collect real-world information to better understand the drug's safety during pregnancy. No new treatments are given; researchers will…

This study will observe about 477 current or former smokers in Brazil to see how well lung cancer screening works in a region where other lung diseases are common. The goal is to find out how often screening gives false alarms, which can lead to extra tests and worry. No new trea…

This study interviews about 85 lung cancer patients and 15 doctors to learn what helps or hinders patients from continuing a targeted pill called osimertinib after surgery. The goal is to identify barriers like side effects, costs, or communication issues, and facilitators like s…

This study will review medical records of about 240 adults in Kazakhstan with HER2-positive metastatic breast cancer to understand which treatments doctors use and how well they work. Researchers want to learn how long patients live without their cancer getting worse. This is an …

This study will observe about 109 women in Gulf countries who have a specific type of advanced breast cancer (HR-positive, HER2-low or ultra-low) and are taking the drug trastuzumab deruxtecan (T-DXd) after hormone therapy stopped working. Researchers will track how long the canc…

This study will follow about 2,000 people in China who have a specific type of lung cancer (EGFR-mutated) and have had surgery. After surgery, they take a targeted pill (EGFR-TKI) to try to prevent the cancer from coming back. Researchers will track how long patients live and how…

This study aims to understand genetic changes in metastatic prostate cancer and how they affect patient outcomes. It will involve 100 adults in Brazil who are receiving standard palliative therapy. Researchers will analyze tumor and blood samples to identify key mutations, but no…