Astrazeneca

This study tested whether adding a new drug called AZD5462 to the standard medicine dapagliflozin could help people with both heart failure and moderate kidney disease. The trial was stopped early and only included 8 participants. The main goal was to see how the drug combination…

This study tested a drug called sodium zirconium cyclosilicate (SZC) to see if it could slow down chronic kidney disease (CKD) in people who also have high potassium levels or are at risk for it. Over 1,100 adults with moderate-to-severe CKD took SZC or a placebo alongside their …

This study was designed to check the long-term safety of the drug brazikumab in people with moderate to severe Crohn's disease. It included 18 adults who had already taken part in an earlier study. The main goal was to track side effects and lab results. However, the study was st…

This early-stage trial tested a new drug called AZD0022 in 17 people with advanced solid tumors (like lung, pancreatic, or colorectal cancer) that have a specific KRASG12D mutation. The study was stopped early, but researchers were checking if the drug is safe and shrinks tumors …

This study tested a combination of the targeted drug osimertinib and chemotherapy as a first treatment for people with advanced non-small cell lung cancer that has uncommon EGFR mutations. The goal was to see if the combo could shrink tumors and delay cancer growth. However, the …

This study tested a drug called benralizumab in 295 adults with severe nasal polyps and chronic sinusitis. The goal was to see if it could shrink polyps and improve symptoms like nasal blockage and loss of smell. The study was stopped early, but the results may still help underst…

This study tested an experimental drug called AZD3427 to see if it could improve blood flow to the kidneys in people with heart failure and reduced kidney function. Only 10 participants were planned, but the study was terminated early. The main goal was to measure changes in kidn…

This study followed 83 adults with advanced lung cancer who were starting standard treatments. The goal was to collect information to help develop a digital tool that can identify patients at risk for pneumonitis, a lung inflammation that can be a side effect of cancer therapy. T…

This early-stage study aimed to see if a drug called ceralasertib changes how the body processes three other cancer drugs (Drug X, Y, and Z) in people with advanced solid tumours. Only one person took part before the study was stopped early. The main goal was to measure drug leve…

This study tested the safety of a new drug called AZD0233 in healthy people aged 18 to 50. The goal was to see if it caused side effects and how the body processes it. The study was stopped early, and no treatment was given for any disease.

This study was designed to collect information about Chinese patients with nonalcoholic steatohepatitis (NASH) and liver scarring. Researchers aimed to describe patient characteristics, how they are diagnosed and treated in real life, and their knowledge about the disease. Over 1…

This study looked at adults with severe uncontrolled asthma in Germany to see how well their asthma was controlled over 12 months. Participants used a simple questionnaire called AIRQ® to track symptoms, medication use, and risk of flare-ups. The goal was to gather real-world inf…

This study aimed to find out how often a rare heart condition called transthyretin amyloidosis cardiomyopathy (ATTR-CM) occurs in Russian patients with a common type of heart failure. Researchers planned to review medical records of 1,770 patients and then examine those with high…