Asan Medical Center

This study tests three different flu vaccines in 60 adults with blood cancers like leukemia or lymphoma, including those who had a stem cell transplant or CAR-T therapy. The goal is to see which vaccine triggers the strongest immune response. Results will help doctors choose the …

This study tests a new three-drug combination (irpagratinib, atezolizumab, and bevacizumab) in people with advanced liver cancer that cannot be removed by surgery. The goal is to see if the combination is safe and can shrink or control tumors. About 33 adults with a specific gene…

This study tests the chemotherapy drug temozolomide in people with advanced gastrointestinal stromal tumors (GIST) that lack a key enzyme called SDH. About 29 adults will receive the drug to see if it shrinks tumors and is safe. The goal is to control the disease, not cure it.

This study tests whether adding the drug cilostazol to standard stroke treatment can prevent early neurological worsening or another stroke within 180 days. It involves 2,340 adults who have had a stroke caused by narrowing of a major artery in the brain or neck. Participants rec…

This study is for people with stomach cancer that has spread to the lining of the belly and causes fluid buildup (ascites). It tests a combination of three drugs: lenvatinib, nivolumab, and chemotherapy. The goal is to see if this combination can help control the cancer and impro…

This study tests whether transplanting healthy gut bacteria (fecal microbiota transplant) along with the immunotherapy drug nivolumab can shrink tumors in people with advanced solid cancers that stopped responding to prior immunotherapy. About 50 adults with advanced, unresectabl…

This study tests an oral form of paclitaxel (Liporaxel) in 28 adults with advanced gastrointestinal stromal tumors (GIST) that no longer respond to three standard drugs (imatinib, sunitinib, regorafenib). Only patients whose tumors have low levels of a protein called P-glycoprote…

This study compares two pacemaker settings in 440 adults with sick sinus syndrome and a slow heart signal. One group gets a newer method that paces the heart's natural electrical system, while the other uses a standard approach that minimizes pacing. The goal is to see which redu…

This study tests whether a personalized blood-thinning plan (shorter dual therapy followed by one drug alone) is safer and just as effective as the standard approach for people with coronary artery disease who have received a stent guided by imaging. About 3,944 adults will be fo…

This study tests a combination of two drugs, rivoceranib and paclitaxel, in people with advanced gastrointestinal stromal tumors (GIST) that have a specific marker (high P-glycoprotein) and have stopped responding to three standard treatments. The goal is to see if this combo can…

This study tests whether giving a combination of three chemotherapy drugs (docetaxel, oxaliplatin, and S-1) before surgery can help remove stomach cancer that has spread to nearby tissues or lymph nodes. About 63 adults with advanced stomach cancer that cannot be fully removed by…

This study tests the drug lenvatinib in people with advanced gastrointestinal stromal tumors (GIST) that have stopped responding to three standard treatments. The goal is to see if lenvatinib can shrink or stabilize the tumors and to check for side effects. About 48 adults will t…

This study is testing a wearable ECG patch (MEMO Patch) to see if it can detect hidden atrial fibrillation—an irregular heartbeat that raises stroke risk—in 100 people who had a stroke with no known cause. Participants wear the patch for up to 14 days at home, and results are com…

This study is testing whether a special PET scan called FES PET/CT can better detect cancer that has spread to distant parts of the body in people with a certain type of stage III breast cancer. The cancer must be low-grade and estrogen receptor-positive. About 85 adults will rec…

This study tests whether a shorter, safer MRI scan can find returning liver cancer as well as the usual CT scan. It involves 455 adults who have been cancer-free for at least two years after treatment. The goal is to reduce radiation and contrast dye risks while still catching ca…

This study tests whether a single iron infusion (ferric carboxymaltose) can safely raise hemoglobin levels in 330 adults with advanced stomach cancer who have iron-deficiency anemia and are starting palliative chemotherapy. The goal is to see if treating the anemia helps patients…

This study tests whether a smartphone-based rehab platform can help adults who have been in the intensive care unit (ICU) recover their strength, thinking skills, and quality of life. About 70 participants from two hospitals in South Korea will use the app daily for up to 30 minu…

This study looks at how gut bacteria affect cancer immunotherapy in people with advanced solid tumors. It has two parts: first, identifying bacterial markers linked to treatment response; second, testing whether fecal transplants from healthy donors can make immunotherapy work be…

This study is a registry that will follow 400 people with mitral stenosis (a narrowed heart valve) who are getting a procedure called percutaneous mitral balloon commissurotomy (PMBC). The goal is to learn about their outcomes and find the best way to size the balloon used during…

This study aims to understand how the immune system and genes change in people with advanced liver cancer during immunotherapy. Researchers will collect blood and tumor samples from 50 participants before and during treatment. The goal is to find biomarkers that predict how well …

This study follows over 500 adults with type 2 diabetes who had a heart CT scan years ago. Researchers will repeat the scan to see how plaque builds up in heart arteries over time and identify factors that increase risk. The goal is to better understand heart disease in diabetes,…