ULCERATIVE COLITIS

This study tested a new medicine called VE202 in people with mild-to-moderate ulcerative colitis, a condition that causes inflammation and sores in the colon. The goal was to see if VE202 could reduce inflammation and improve symptoms compared to a placebo. The trial was stopped …

This study tested an experimental oral drug, PF-07054894, in 44 adults with mild to severe ulcerative colitis. The goal was to see if it could safely reduce inflammation and improve symptoms. The trial was terminated early, so results are limited. Participants had active disease …

This study tested a drug called vixarelimab in 79 people with moderate to severe ulcerative colitis who had not responded well to other treatments. The goal was to see if the drug could help control the disease and reduce symptoms like diarrhea and bleeding. However, the trial wa…

This study tested a new drug called efavaleukin alfa for people with moderate to severe ulcerative colitis, a chronic bowel disease. Participants received one of three doses of the drug or a placebo for 12 weeks, with an option to continue treatment for up to a year. The goal was…

This study tested whether a new drug called AVT16 works as well as the approved drug Entyvio for people with moderate to severe ulcerative colitis. The trial planned to include 301 adults aged 18 to 80. However, the study was terminated early, so results are limited.

This study aimed to see how well the drug tofacitinib works for people with moderate to severe ulcerative colitis in everyday medical practice in Switzerland. It included 18 adults who were already prescribed the drug. The study was stopped early, but researchers still collected …

This study tested whether a bile acid supplement called UDCA could reduce inflammation and improve quality of life in people with pouchitis, a complication after ulcerative colitis surgery. Only 2 participants were enrolled before the study was stopped early. The goal was to see …

This study tested a stem cell product called Remestemcel-L for people with severe ulcerative colitis that did not get better with standard treatments. The goal was to see if injecting these cells into the colon was safe and could help patients avoid surgery or stronger drugs. Onl…

This study tested whether statins, a common cholesterol medication, could change the gut bacteria of people with ulcerative colitis to a healthier type and reduce disease activity. It included 177 adults with mild to moderate colitis or Crohn's disease. The trial was terminated e…

This study looked at the long-term safety of an experimental drug called efavaleukin alfa for people with moderate to severe ulcerative colitis. It was designed for patients who had already completed a one-year study and might benefit from continued treatment. However, the study …