TRIPLE-NEGATIVE BREAST CARCINOMA

This study compares giving a shorter, higher-dose radiation schedule (hypofractionated radiotherapy) either before or after breast cancer surgery. The goal is to see which timing is safer and works better for different types of non-metastatic breast cancer. About 120 adults with …

This study tests whether adding the drug darolutamide to standard chemotherapy and immunotherapy before surgery can shrink tumors more effectively in people with early-stage androgen receptor positive triple-negative breast cancer. About 51 participants will receive either standa…

This study is testing whether certain breast cancer patients who respond extremely well to initial drug therapy can safely skip surgery or radiation. For HER2-positive and triple-negative breast cancers, if a biopsy shows no cancer left after drug treatment, patients receive only…

This study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps the immune syst…

This study looks at whether cutting calories while getting focused radiation (SABR) before surgery can shrink breast tumors more than radiation alone. About 80 adults with early-stage breast cancer will be randomly assigned to one of two groups. The goal is to see if the diet hel…

This study looks at whether a healthy eating plan called the MIND diet can reduce memory and thinking problems (chemobrain) and other symptoms like fatigue and anxiety in women with stage II-III triple-negative breast cancer during chemotherapy. About 60 women will be randomly as…

This study tests whether a 10-week stress reduction program is practical and helpful for people with triple negative breast cancer. The program teaches relaxation, coping skills, and communication, and also connects participants with social services for needs like transportation …

This study tests whether a computer-generated character can effectively educate cancer patients about genetic testing, compared to a human genetics counselor. The goal is to see if this approach increases testing rates, especially for minority and rural patients who often lack ac…