TREATMENT

This study tested a new way to aim radiation at pancreatic cancer that hasn't spread. The goal was to see if targeting areas where the cancer tends to come back could help people live longer without the disease getting worse. 96 adults with locally advanced pancreatic cancer took…

This study tested two different radiation doses (lower vs. higher) combined with chemotherapy in 119 people with locally advanced pancreatic cancer. The goal was to see which dose helps people live longer without the cancer growing, while also causing fewer side effects. Particip…

This study tested the safety and effectiveness of injecting the antifungal drug fluconazole directly into the cornea to treat fungal keratitis, a serious eye infection. Forty patients with lab-confirmed fungal keratitis that was sensitive to fluconazole took part. The approach ai…

This study tested whether special clear aligners can correct jaw growth in children aged 10-16 with a type of overbite called Class II malocclusion. 21 participants were randomly assigned to one of three treatments: aligners with or without a bite-opening feature, or standard twi…

This study tested a short therapy called Acceptance and Commitment Therapy (ACT) for 49 people with HIV who were heavy drinkers. The therapy uses mindfulness and personal values to help reduce drinking and improve HIV medication adherence. Researchers measured drinking days, alco…

This study tested two methods of washing out the jaw joint (arthrocentesis) in 30 adults with painful, stiff jaws from TMJ disorder. One method used a single needle, the other used a small tube (catheter) to help flush the joint. The goal was to see which approach better reduced …

This study tested whether an injection made from a patient's own blood (i-PRF) can reduce pain and improve jaw opening in people with temporomandibular joint (TMJ) disorders. 40 adults were split into two groups: one got standard joint washing plus the i-PRF injection, the other …

This study tested whether injecting platelet-rich plasma (a concentration of healing cells from your own blood) into the wound after pilonidal sinus surgery helps it heal better. Forty people with chronic or recurrent pilonidal sinuses took part. Researchers measured wound healin…

This study tested two sleep medications (suvorexant and zolpidem) against a placebo in 40 adults with progressive supranuclear palsy (PSP), a brain disease that disrupts sleep. Each person tried all three options for one week each, with a week off in between. The goal was to see …

This study looked at 87 people with frozen shoulder to see if their level of central sensitization (a condition where the nervous system is extra sensitive to pain) affected how well they responded to a shoulder injection. Researchers measured central sensitization using a questi…

This study looked at what makes it easier or harder for people with migraine and healthcare workers in Thailand to use a new preventive treatment called eptinezumab. Researchers interviewed 30 participants, including patients and providers, and tracked migraine symptoms over 6 mo…