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Can a nerve block cure your headache? new study investigates

NCT ID NCT07487649

Knowledge-focused Sponsor: Sultan 1. Murat State Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 10, 2026 · Updated 2 times

Summary

This study aims to find out which patient factors influence how well a nerve block works for medication-overuse headache. Researchers will give 70 adults an ultrasound-guided injection and track their pain and medication use for one month. The goal is to better predict who will benefit most from this treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70 people

The number who actually took part.

Started

Mar 2026

Finished

May 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who underwent ultrasound-guided greater occipital nerve block with a diagnosis of medication-overuse headache at Edirne Sultan 1. Murat State Hospital

Ages

18 to 65 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Diagnosis of medication-overuse headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) * Diagnosis of medication-overuse headache associated with the use of triptans or nonsteroidal anti-inflammatory drugs * Previous diagnosis of chronic migraine or chronic tension-type headache according to the ICHD-3 criteria Exclusion Criteria: * History of severe head or neck trauma or previous neurosurgical intervention * Presence of a severe psychiatric disorder (e.g., severe depression, schizophrenia) * History of infectious disease, chronic inflammatory disease, or malignancy * Previous diagnosis of secondary headache * History of substance abuse * Pregnancy or breastfeeding * History of an additional neurological disorder (e.g., cerebrovascular disease, multiple sclerosis) * Difficulty with cooperation * Presence of a concomitant systemic disease that may affect quality of life (e.g., congestive heart failure, chronic kidney disease, chronic liver disease, pulmonary disease, uncontrolled diabetes, or peripheral vascular disease)

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Conditions

The condition(s) this trial relates to.

Headache Headache Disorders, Secondary migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Greater occipital nerve block Headache Medication overuse headache Treatment

Contacts and locations

Locations

  • Sultan 1. Murat State Hospital

    Edirne, 22030, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.