HEADACHE

This study tests whether adding a daily pill (amitriptyline) to online cognitive behavioral therapy (CBT) works better than CBT alone for preventing migraines in children aged 7-17. Researchers will track headache days and disability over time. The goal is to find the best first-…

This study tests a lifestyle behavior program to help people with chronic migraine reduce how often and how severely their headaches happen. Researchers will also look for biological markers linked to improvement. The goal is to see if the program is practical and liked by partic…

This study tests whether a computer algorithm can predict the best way to stimulate the brain to relieve headaches and body pain in veterans with Gulf War Illness. About 140 veterans will receive active rTMS treatment, and the algorithm's predictions will be checked against their…

This study tests whether a numbing injection through the nose can better relieve severe headaches caused by a brain bleed (subarachnoid hemorrhage). About 40 adults with a secured aneurysm will receive either the nerve block plus standard pain meds or standard meds alone. The goa…

This study tests whether delivering lidocaine (with or without steroids) directly into an artery in the brain can relieve the severe headaches that often follow a type of stroke called subarachnoid hemorrhage. The goal is to reduce pain and the need for strong opioid drugs. About…

This study is testing a mind-body program delivered by nurses to help children and teens with migraine have fewer headache days. The program combines different treatment parts to find the best approach. About 260 kids with migraine will take part. The goal is to see if this progr…

This study tests a noninvasive, personalized brain stimulation treatment (TMS) for people aged 18-65 with chronic symptoms after a mild concussion or brain injury, such as headache, dizziness, brain fog, or anxiety. Participants will have a 66% chance of receiving active TMS and …

This pilot study tests a new program called CRISP to help young adults (ages 18-29) recover from concussion and reduce headaches. About 40 participants will be randomly assigned to the program or usual care. The study measures how acceptable the treatment is and tracks headache s…

This study looked at 38 operating room nurses to see if wearing a surgical mask or an N95 mask made a difference in physical symptoms caused by surgical smoke. Nurses wore each type of mask for four weeks and reported symptoms like headache, fatigue, and muscle pain. The results …

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce chronic headaches in people who had a mild traumatic brain injury. Researchers will track headache changes, sleep, and daily function in 60 adults aged 18–55. The goal is to find a drug-fre…

This study looks at whether a 16-week supervised aerobic exercise program, combined with a session on pain education, can help women aged 18 to 48 who have migraines. Researchers will measure changes in headache-related disability, pain sensitivity, and quality of life. The goal …

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can prevent or reduce headaches after a brain aneurysm repair procedure. About 440 adults who are scheduled for stent-assisted coiling will wear the device for 30 minutes twice a day, st…

This study tests whether a numbing injection in the face can reduce severe headaches and the need for strong painkillers after a brain bleed. About 195 adults who had a brain bleed will receive either the active injection or a placebo. The goal is to see if this approach safely c…

This study is for people with medication-overuse headache, a condition where taking too much pain medicine makes headaches worse. Researchers want to find out which patient factors (like age or headache history) affect how well a nerve block injection works. 70 adults will get an…

This study is gathering information from 50,000 people with headaches to create a better system for diagnosing and treating them. Researchers will collect medical history, treatment data, and biological samples to understand different headache types. The goal is to help doctors m…