HEADACHE

This study aims to find the most effective way to prevent migraines in children and teens using telehealth. Researchers will compare cognitive behavioral therapy (CBT) delivered via video calls alone versus CBT combined with the medication amitriptyline. The trial involves 400 yo…

This UCLA study is testing a personalized, non-invasive brain stimulation treatment for people who still have symptoms like headaches, dizziness, fatigue, and brain fog months after a concussion. Researchers will use MRI scans to map each person's brain and then apply magnetic pu…

This study compared how well surgical masks and N95 masks protect operating room nurses from physical symptoms caused by surgical smoke. Thirty-eight nurses wore each type of mask during their shifts and reported their symptoms. The results showed N95 masks were better at reducin…

This study is testing whether a targeted nerve block injection can safely reduce severe headaches in people recovering from a specific type of brain bleed (aneurysmal subarachnoid hemorrhage). The goal is to see if this injection can lessen patients' need for strong opioid painki…

This study is testing whether a gentle electrical stimulation device worn on the ear can reduce headaches that occur after a procedure to repair a brain aneurysm. Researchers will compare the real stimulation to a fake (sham) version in 440 adults to see if it safely lowers heada…

This study tests whether a non-invasive brain stimulation technique called rTMS can help reduce chronic headaches that develop after mild traumatic brain injury (concussion). Researchers will give magnetic stimulation treatments to 60 adults who have had persistent headaches for …

This small pilot study is testing a new 6-session online therapy program called CRISP for young adults (ages 18-30) who still have headaches and other symptoms after a concussion. The program, based on a therapy used for chronic pain, helps people understand and express emotions …

This study is testing a new lifestyle and behavior program to help manage chronic migraine. Researchers will enroll 60 adults who have had chronic migraine for at least a year to see if the program is practical and acceptable. The main goals are to check if people can stick with …

This study is testing if a special nasal spray that numbs a nerve cluster can help reduce the severe headaches people get after a type of brain bleed called a subarachnoid hemorrhage. Researchers want to see if adding this spray to standard pain medication works better than medic…

This study is testing if a medication infusion directly into a brain artery can relieve the severe headaches that follow a type of brain bleed called a subarachnoid hemorrhage. Researchers will give 15 patients either lidocaine, lidocaine with a steroid, or no infusion during a s…

This study is testing whether a supervised aerobic exercise program, combined with education about pain, can help women with migraines. It will compare this approach to general recommendations for home-based physical activity. The goal is to see if exercise can reduce migraine-re…

This study is testing a mind-body skills program delivered by nurses to help children and teens (ages 10-17) with migraines reduce their headache days. Researchers are comparing different versions of the program to find the most effective combination of coaching sessions, home pr…

This study aims to understand why some people with medication-overuse headaches respond better than others to a specific nerve block injection. Researchers will observe 70 adults who receive an ultrasound-guided injection to block a nerve in the back of the head. They will collec…

This is a large, long-term observational study that aims to collect detailed information from 50,000 people with headaches over 10 years. The goal is to better understand the different causes and patterns of headaches by tracking patients' symptoms, treatments, and health data. R…