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Clear aligners take on overbites: a kinder option for kids?

NCT ID NCT07420270

Disease control Sponsor: University of Malaya Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compared clear mandibular advancement aligners to traditional twin-block braces for correcting Class II Division 1 malocclusion (overbite) in 21 children aged 10-16. Participants were split into three groups and followed for 6 months. The goal was to see if the aligners could improve jaw and teeth alignment while being more comfortable and less noticeable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mandibular Advancement Aligner (dental device)
What this could lead to
If successful, this could offer a more comfortable and less visible alternative to traditional braces for correcting overbites in children.
What could go wrong
This is a small, early-stage trial with only 21 participants, so results may not apply to everyone. The aligners may not work as well as standard appliances, and long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

21 people

The number who actually took part.

Started

Jul 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

11 to 16 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Cervical Vertebrae Maturity: CS3-CS4 (Growing participants) * Chronological age: 10-14 years old (Female), 12-16 years old (Male) * Average or reduced lower anterior facial height (LAFH\<57%) * Mild to moderate skeletal Class II (4°\<ANB\<9°) * Retrognathic mandible (SNB\<78°) * Increased overjet (7mm≤OJ≤11mm) * Increased overbite by more than 30% * Molar relationship by more than ½ unit Class II bilaterally * Mild to moderate crowding Exclusion Criteria: * Participant with an anterior open bite * Participant with syndromic dentofacial anomalies * Participant with a previous history of orthodontic intervention * Participant with signs and symptoms of temporomandibular disorder * Participant with severe facial asymmetry (Deviation ≥4mm) * Not being consented to by both parents and participants * Poor quality of pre-treatment Lateral Cephalometric records * Participant with mental or physical disabilities affecting the ability to wear an appliance

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Conditions

The condition(s) this trial relates to.

Malocclusion, Angle Class II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Growth modification Treatment

Contacts and locations

Locations

  • Faculty of Dentistry

    Kuala Lumpur, Kuala Lumpur, 50603, Malaysia

More trials for these conditions

Other studies related to the condition(s) this trial covers.