Frozen shoulder study: why some patients respond better to injections
NCT ID NCT07124689
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 87 people with frozen shoulder to see if their level of central sensitization—a condition where the nervous system is extra sensitive to pain—affected how well they responded to a shoulder injection. Researchers measured central sensitization using a questionnaire and tracked pain levels after the injection. The goal was to better understand why some patients improve more than others.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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87 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Dec 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who underwent ultrasound-guided glenohumeral intra-articular injection with a diagnosis of frozen shoulder at Edirne Sultan 1. Murat State Hospital
- Ages
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18 to 75 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Being between 18 and 75 years of age * More than one-third of the active and passive movement of the painful shoulder is limited in two or more planes * Having pain and limited movement in the shoulder for 3-12 months Exclusion Criteria: * Having bilateral shoulder pain * Patients with incomplete study data * Having cervical radiculopathy * Having a predominant central sensitization syndrome (such as fibromyalgia, chronic fatigue syndrome) * Patients taking antidepressants or anticonvulsants that may affect central sensitization * Having a history of rheumatological disease * Having a history of active malignancy * Patients receiving treatment for active psychiatric disorders * Having a history of trauma and/or surgery in the same shoulder region * Patients who received local shoulder injections and/or physical therapy within the last 3 months * Patients with calcific tendonitis, glenohumeral osteoarthritis, or acromioclavicular joint osteoarthritis on plain radiographs * Having a full-thickness rotator cuff tear on shoulder ultrasound
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sultan 1. Murat State Hospital
Edirne, 22030, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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