TOBACCO SMOKING

This study tests whether starting nicotine replacement therapy (patches, gum, or lozenges) at a specific time in the menstrual cycle helps women quit smoking. About 1,200 women who smoke daily and have regular periods will be assigned to start their quit attempt during the follic…

This study tests a program called MINDSET for veterans with chronic conditions like heart disease or diabetes who smoke or drink too much. Participants receive a mailed packet with personalized health information and a brief motivational phone call. The goal is to see if this app…

This study tests a smoking cessation program in construction companies. Safety managers are trained to help workers quit smoking. The goal is to find the best, most cost-effective way to reduce smoking and improve health. About 608 workers and managers will take part.

This study tests whether cannabidiol (CBD) can reduce cigarette smoking in people with tobacco use disorder. Researchers will give 120 participants either CBD or a placebo twice daily for 56 days, measuring nicotine levels and smoking abstinence. The goal is to find a new way to …

This study tests whether using mobile health (mHealth) tools helps find early signs of oral cancer better than the usual visual exam in rural areas of Varanasi, India. Over 5,000 adults with risk factors like smoking, tobacco use, or age over 40 will be screened. The goal is to c…

This study compares two ways to help people stop smoking and lower their cancer risk. About 5,000 adults who smoke and visit a participating clinic will be assigned to either a program that uses personalized reminders and support (ELEVATE-S) or standard quit-focused care (ELEVATE…

This early study at Johns Hopkins is testing whether cannabidiol (CBD) can reduce stress and nicotine withdrawal symptoms in people who smoke. 90 healthy smokers will take CBD and then be exposed to stress in a lab setting. Researchers will measure mood, stress hormones, and phys…

This study tests whether adding Buteyko breathing exercises to a smoking hygiene program can improve ear and lung function in 40 teens who are regularly exposed to secondhand smoke at home. Participants will learn breathing techniques and ways to reduce smoke exposure. The goal i…

This study tests a smartphone app designed to help pregnant women stop smoking and stay smoke-free after giving birth. The app uses artificial intelligence to personalize tips and includes a support person chosen by the participant. About 790 pregnant smokers in Romania will take…

This study tests whether a daily oral dose of cannabidiol (CBD) can help people stop smoking tobacco. Fifty adults who smoke more than 10 cigarettes a day and want to quit will take CBD during several practice quit attempts. The goal is to see if CBD increases short-term abstinen…

This study enrolls 40 healthy smokers to compare how addictive five new oral nicotine products are compared to their usual cigarettes and Nicorette gum. Participants will use each product in a clinic setting, and researchers will measure their feelings of liking and nicotine leve…

This study looks at how young adults (ages 18-25) who smoke both marijuana and tobacco decide to use each substance when prices change. Researchers will measure cravings after showing pictures of marijuana or tobacco. The goal is to understand patterns of dual use, not to test a …