TOBACCO SMOKING

This study will test whether e-cigarettes or a natural supplement called cytisine can help people who smoke at least 5 cigarettes a day and haven't been able to quit with standard treatments like nicotine patches or counseling. Over 4 years, 6,000 participants will be randomly as…

This study tests a program called PAL that gives hospital patients personalized feedback on smoking, drinking, diet, and exercise. About 788 adults admitted to non-intensive care wards will be randomly assigned to receive the program or usual care. The goal is to see if the progr…

This study will enroll 40 healthy adult smokers to compare how much they crave different tobacco products. Participants will try heated tobacco devices, their usual cigarettes, and nicotine gum in a clinic setting. Researchers will measure their desire to smoke and nicotine level…

This study will enroll 70 adult smokers to compare how appealing and addictive different e-cigarettes are versus their usual cigarettes and nicotine gum. Participants will try each product in a random order during an 8-day stay at a clinic. Researchers will measure how much nicot…

This study will check how addictive two new nicotine pouches are by measuring their effects on the body and how much nicotine gets into the blood. About 40 healthy adults who smoke and also use smokeless tobacco will try the pouches in a clinic. The goal is to understand the abus…

This study looks at how much nicotine enters the blood when people use e-cigarettes compared to regular cigarettes. About 40 healthy adult smokers will try different e-cigarette products in a controlled setting. The goal is to understand nicotine levels and how much people like e…