TOBACCO SMOKING
Clinical trials for TOBACCO SMOKING explained in plain language.
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Mailed nicotine patches and pills: a new way to kick the habit?
Disease control CompletedThis study tested whether mailing free samples of varenicline (Chantix) or nicotine patches and lozenges helps smokers quit. Over 650 daily smokers were randomly assigned to receive a free sample of varenicline, nicotine replacement products, or no medication. Participants comple…
Matched conditions: TOBACCO SMOKING
Phase: PHASE1, PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 23, 2026 11:55 UTC
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New study explores e-cigarettes and nicotine patches to help HIV patients quit smoking
Disease control CompletedThis study tested two methods to help people living with HIV/AIDS in South Africa reduce their cigarette smoking: using e-cigarettes or nicotine replacement therapy (like patches), plus supportive text messages. 106 adults who smoked daily took part. The goal was to see if these …
Matched conditions: TOBACCO SMOKING
Phase: PHASE1 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 22, 2026 12:03 UTC
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Cash for quitting: study tests money as a motivator for homeless smokers
Disease control CompletedThis study tested whether offering financial rewards helps homeless adults quit smoking. 184 participants received smoking cessation coaching and a prescription for varenicline. Half were also given escalating cash rewards for each time they tested negative for smoking over 12 we…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 18, 2026 11:53 UTC
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Can an iPad avatar help you quit smoking?
Disease control CompletedThis study tested a computer program called C-Raven that uses an interactive avatar to help people quit smoking. Participants used an iPad for two 20-minute sessions and could get nicotine replacement therapy and support from a community health worker. The study was small (18 peo…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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Longer Pre-Quit drug course may boost smoking cessation success
Disease control CompletedThis study tested whether taking the smoking-cessation drug varenicline for 4 weeks before quitting, instead of the usual 1 week, helps more people stay smoke-free. 320 smokers were randomly assigned to either the extended or standard pre-quit schedule, and both groups received c…
Matched conditions: TOBACCO SMOKING
Phase: PHASE3 • Sponsor: State University of New York at Buffalo • Aim: Disease control
Last updated Jun 12, 2026 12:06 UTC
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Guam school curriculum aims to curb teen vaping and betel nut use
Prevention CompletedThis study tested a school-based curriculum designed to prevent e-cigarette, tobacco, and betel (areca) nut use among middle school students in Guam. Over 500 students from public schools participated, with some schools receiving the new curriculum and others continuing standard …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: University of Guam • Aim: Prevention
Last updated Jun 22, 2026 12:00 UTC
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New program aims to help HIV patients kick the habit while in hospital
Symptom relief CompletedThis pilot study tested a program for hospitalized people with HIV who smoke. Participants received two computer counseling sessions, nicotine replacement therapy, and follow-up support from a community health worker for up to 8 weeks. The goal was to see if this approach is feas…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 23, 2026 18:03 UTC
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Zapping the brain to kick the habit: new hope for HIV smokers?
Symptom relief CompletedThis small study tested whether a type of brain stimulation called TMS could reduce cigarette cravings and attention to smoking cues in people living with HIV/AIDS. Four participants received either real or fake (sham) stimulation over four sessions. The goal was to see if TMS co…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Gopalkumar Rakesh • Aim: Symptom relief
Last updated Jun 15, 2026 19:04 UTC
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Heated tobacco vs. cigarettes: which pollutes the air less?
Knowledge-focused CompletedThis study measured harmful chemicals in the air after adults used either a heated tobacco product (ploom) or regular cigarettes in a sealed room. Researchers tracked over 20 pollutants like nicotine, formaldehyde, and benzene. The goal was to see how the two products differ in s…
Matched conditions: TOBACCO SMOKING
Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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Could sedatives help smokers quit? early study tests the idea
Knowledge-focused CompletedThis small, early-phase study tested whether a single dose of sedatives like ketamine, midazolam, or dexmedetomidine could reduce cigarette cravings and smoking in 20 daily smokers. Participants received one of these drugs or a placebo (saline) and reported their cravings, withdr…
Matched conditions: TOBACCO SMOKING
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:00 UTC
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New program boosts smoking cessation know-how in mental health clinics
Knowledge-focused CompletedThis study tested a program to help staff at community mental health clinics better support their patients in quitting smoking. Researchers worked with 91 clinic staff to see if training and support could improve their knowledge and confidence in delivering evidence-based smoking…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC