Mailed nicotine patches and pills: a new way to kick the habit?
NCT ID NCT04525755
First seen Feb 19, 2026 · Last updated Jun 22, 2026 · Updated 16 times
Summary
This study tested whether mailing free samples of varenicline (Chantix) or nicotine patches and lozenges helps smokers quit. Over 650 daily smokers were randomly assigned to receive a free sample of varenicline, nicotine replacement products, or no medication. Participants completed surveys over six months and daily diaries for the first month. The goal was to see if simply offering free medication by mail increases quit rates.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
varenicline (Chantix) and nicotine replacement therapy (patches and lozenges)
What this could lead to
If successful, this approach could make it easier for smokers to try quitting by getting free medication samples by mail, without needing a doctor visit.
What could go wrong
This is an early-phase study, so results may not be conclusive. The sample is small and self-reported, so actual quit rates could be lower.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.