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New study explores e-cigarettes and nicotine patches to help HIV patients quit smoking

NCT ID NCT06169813

Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two methods to help people living with HIV/AIDS in South Africa reduce their cigarette smoking: using e-cigarettes or nicotine replacement therapy (like patches), plus supportive text messages. 106 adults who smoked daily took part. The goal was to see if these approaches were practical and could help cut down or quit smoking, which can improve their long-term health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

106 people

The number who actually took part.

Started

Apr 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult PLWHA CC smokers; * Speaks Afrikaans, or Xhosa, or English; * reports daily CC smoking (≥ 5 CPD); * Owns any type of mobile phone; * interested in reducing CC smoking but not necessarily trying to quit; * Receives HIV/AIDS care in one of the eight selected clinics follow-up rates. Exclusion Criteria: * are pregnant or breastfeeding; * unable to provide consent; * used tobacco products other than CC in the past 2 weeks (e.g., EC, cigarillo); * currently engaged in an attempt to quit CC smoking; * current major depressive or manic episode, current psychotic disorder, past-year suicide attempt, or current suicidal ideation with plan or intent. plan or intent.

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Conditions

The condition(s) this trial relates to.

AIDS Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tobacco smoking

Contacts and locations

Locations

  • South African Medical Research Council (SAMRC)

    Cape Town, 7501, South Africa

More trials for these conditions

Other studies related to the condition(s) this trial covers.