New study tests if menstrual cycle timing boosts Quit-Smoking success
NCT ID NCT05515354
First seen Mar 29, 2026 · Last updated Jun 22, 2026 · Updated 14 times
Summary
This study tests whether starting nicotine replacement therapy (patches, gum, or lozenges) at a specific time in the menstrual cycle helps women quit smoking. About 1,200 women who smoke daily and have regular periods will be assigned to start their quit attempt during the follicular phase, luteal phase, or at their usual time. The goal is to see if cycle-timed quitting leads to higher abstinence rates.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre for Addiction and Mental Health, Nicotine Dependence Clinic
RECRUITINGToronto, Ontario, M6J 1H4, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nicotine replacement therapy (patch, gum, lozenge)
What this could lead to
If successful, this could show that timing quit attempts to the menstrual cycle improves smoking cessation rates in women.
What could go wrong
This is a large Phase 4 trial, but the effect may be small or not generalizable to all women. Success depends on adherence and individual cycle variability.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.