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CBD shows promise in helping smokers quit – new trial underway

NCT ID NCT06218056

First seen Apr 22, 2026 · Last updated Jun 20, 2026 · Updated 13 times

Summary

This study tests whether cannabidiol (CBD) can reduce cigarette smoking in people with tobacco use disorder. Researchers will give 120 participants either CBD or a placebo twice daily for 56 days, measuring nicotine levels and smoking abstinence. The goal is to find a new way to help people quit smoking when current treatments fail.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CRI-Help, Inc.

    RECRUITING

    North Hollywood, California, 91601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cannabidiol (CBD)

What this could lead to

If it works, this could offer a new option to help people cut down or quit smoking, especially those who haven't succeeded with existing treatments.

What could go wrong

This is a mid-stage trial with only 120 participants, so results may not apply to everyone. CBD's effectiveness for smoking reduction is not yet proven, and side effects are possible.

Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Cessation Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.