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Can CBD help smokers beat stress and cravings?

NCT ID NCT07001930

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This early study at Johns Hopkins is testing whether cannabidiol (CBD) can reduce stress and nicotine withdrawal symptoms in people who smoke. 90 healthy smokers will take CBD and then be exposed to stress in a lab setting. Researchers will measure mood, stress hormones, and physical responses to see if CBD helps.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Behavioral Pharmacology Research Unit

    RECRUITING

    Baltimore, Maryland, 21224, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cannabidiol (CBD)

What this could lead to

If it works, this could point toward a way to help people quit smoking by reducing stress and withdrawal discomfort.

What could go wrong

This is a very early Phase 1 study with only 90 people, so results may not apply broadly. CBD may not significantly affect stress or withdrawal, and side effects are possible.

Conditions

The condition(s) this trial relates to.

nicotine dependence Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.