SYSTEMIC SCLEROSIS

This study tested whether using a stem cell transplant right away is better than starting with standard immune-suppressing drugs for people with early, severe scleroderma. Sixty adults with the disease were randomly assigned to one of two treatment strategies. The goal was to see…

This early-phase study tested a drug called nemolizumab in 6 adults with systemic sclerosis, a rare disease that causes skin to harden and tighten. The main goal was to see if the drug could reduce skin thickness over 24 weeks, and to check for side effects. Results will help dec…

This study looked at whether a chest ultrasound can find early signs of lung disease in people with systemic scleroderma, a condition that often leads to deadly lung scarring. Current methods like CT scans have drawbacks, so researchers tested ultrasound in 30 patients without kn…

This study tested a self-management program for people with scleroderma, a chronic disease that can cause pain, fatigue, and skin problems. The program includes educational videos and group video calls led by trained peers. Researchers wanted to see if it helps patients feel more…

This study looked at 214 people with systemic sclerosis (scleroderma) to find out how often calcium deposits form in the hands and feet. Researchers used X-rays to detect these deposits, which are hard to see with just a physical exam. They also checked whether these deposits are…

This study compared two different machines that measure how well the lungs transfer gas in people with systemic sclerosis and lung disease. Nine participants took both tests in a random order. The goal was to see if the devices give different results, which could affect how docto…

This study looked at whether certain immune system markers (autoantibodies) can help predict the course of pulmonary arterial hypertension (PAH), a serious lung condition. Researchers examined blood samples from 629 adults with different types of PAH, including those linked to HI…

This study followed 56 people with systemic sclerosis (scleroderma) who also have a serious lung condition called diffuse infiltrating pneumonia. Researchers measured lung function at 12 and 24 months to see how the disease changes over time and to identify factors that might pre…

This study looked at the experiences of 50 family caregivers of people with systemic sclerosis, a rare chronic disease. Researchers used questionnaires to understand caregivers' quality of life, health, and relationship with the patient. The goal is to learn how to better support…