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Immune clues may predict lung disease outcomes

NCT ID NCT01208792

First seen Oct 31, 2025 · Last updated Jun 18, 2026 · Updated 38 times

Summary

This study looked at 629 adults with different types of pulmonary arterial hypertension (PAH), including those linked to HIV, heart defects, and connective tissue diseases. Researchers checked for specific antibodies that might help predict how the disease will progress. The goal was to better understand the role of the immune system in PAH, not to test a new treatment.

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Contacts and locations

Locations

  • Internal Medicine Department, Claude Huriez Hospital

    Lille, 59000, France

  • Internal Medicine Department, Cochin Hospital

    Paris, 75014, France

  • Pneumology Department, Antoine Béclère Hospital

    Clamart, 92000, France

Conditions

The condition(s) this trial relates to.

AIDS chronic thromboembolic pulmonary hypertension congenital heart disease connective tissue disorder HIV infectious disease idiopathic pulmonary arterial hypertension mixed connective tissue disease pulmonary arterial hypertension Sjogren syndrome systemic lupus erythematosus systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.