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New MRI method could spot lung damage without radiation

NCT ID NCT05204355

First seen May 13, 2026 · Last updated Jun 23, 2026 · Updated 6 times

Summary

This study tested whether MRI can detect and monitor interstitial lung disease (lung scarring) in people with scleroderma. Twenty-five adults with scleroderma underwent both MRI and CT scans. A subset also breathed in a special xenon gas to see how well their lungs exchange oxygen. The goal was to see if MRI could replace CT scans, which use radiation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI and hyperpolarized xenon gas

What this could lead to

If successful, MRI could become a safer, radiation-free way to detect and track lung scarring in scleroderma patients.

What could go wrong

This is a small, completed study with only 25 participants. MRI may not be as accurate as CT scans, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

diffuse scleroderma pulmonary systemic sclerosis scleroderma systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.