SURGERY

This study tested whether giving chemotherapy and radiation before surgery could better control aggressive brain tumors called glioblastoma. The approach aimed to delay tumor regrowth compared to standard treatment. The trial was terminated early with only 2 participants enrolled…

This study tested whether using a special finger sensor during major surgery could help doctors better monitor patients' blood levels. The goal was to see if this noninvasive monitoring could lead to smarter decisions about when to give blood transfusions and improve recovery aft…

This study tested whether a program to help smokers quit for four weeks before major surgery could reduce complications after the operation. It involved 251 adult smokers scheduled for cancer or other high-risk surgeries. Researchers compared a structured quit program against sim…

This study tested if a new, clearer guide for patients and nurses on how to shower before surgery could make skin cleaner and help prevent infections at the surgical site. Researchers first interviewed patients and healthcare workers to design the guide, then planned to see if it…

This study compared two methods for controlling pain after laparoscopic colon surgery. Researchers tested whether a spinal fluid injection or a nerve block in the back provides better pain relief and faster recovery. The trial involved 116 patients and measured pain levels, medic…

This study compared two drugs used to reverse muscle paralysis after anesthesia in children having appendix surgery. Researchers wanted to see if one drug (sugammadex) helped children wake up faster, regain bowel function sooner, and leave the hospital quicker than the standard d…

This study compared two approaches to recovery after open-heart surgery. One group followed strict movement restrictions (like not lifting over 5-8 pounds). The other group was told to let their pain and discomfort guide their activity. Researchers wanted to see if the more flexi…

This study aimed to find out if measuring the thickness of a protective layer lining blood vessels (called the glycocalyx) before heart surgery could help predict which patients might develop serious complications after their operation. Researchers planned to enroll 130 patients …

This study aimed to see if remote monitoring could help predict when patients might have problems recovering from major surgery. It involved 56 adults who tracked their daily exercise and symptoms using wearable devices and logs. The goal was to develop computer algorithms that c…

This study tested a new measurement called RPVi to see if it could better predict when a patient under anesthesia needs extra IV fluids during surgery. It compared RPVi to two existing methods doctors already use. The goal was to gather data to see if this new approach could help…

This study aimed to see if a small balloon placed in the food pipe could safely and accurately measure pressure inside the lungs of patients undergoing chest surgery. Researchers compared these balloon measurements to images from a special belt that shows how the lungs are collap…