SURGERY

This study tested giving chemotherapy and radiation before surgery for people with a newly diagnosed, removable glioblastoma (a fast-growing brain cancer). The goal was to see if this approach could improve tumor control and survival. Only 2 people enrolled before the trial was s…

This study looked at whether a structured smoking cessation program, started four weeks before surgery, could reduce complications in smokers undergoing intermediate to high-risk operations. The trial planned to enroll 251 patients but was terminated early. The goal was to compar…

This study compared two common nerve block techniques—femoral nerve block and suprainguinal fascia iliaca block—for pain after hip fracture surgery. Researchers wanted to see which one reduces pain and the need for painkillers better. The study included 17 adults having hip fract…

This study compared two pain control methods for people having laparoscopic colorectal surgery. One group got a spinal injection of pain medicine, and the other got a nerve block in the back. The goal was to see which method reduced the need for additional painkillers. The study …

This study looked at whether letting patients manage their own sternal precautions after heart surgery leads to better quality of life without increasing pain or complications. Ten adults who had heart surgery were followed for up to a year. The goal was to see if a self-managed …

This study compared two medications, sugammadex and neostigmine, used to reverse muscle relaxants after surgery in children aged 2-17 having their appendix removed. The goal was to see which drug helped children leave the operating room faster and recover bowel function sooner. T…

This study looked at whether a new measure called RPVi can help doctors predict when surgery patients need more fluids. It included 63 adults having planned surgeries with general anesthesia. The study was stopped early, and its goal was to compare RPVi to standard methods like s…

This study aimed to see if remote monitoring devices could help predict how well patients recover after major surgery. Researchers planned to track 56 adults before and after their operation using wearable sensors. The study was terminated early, so results are limited.

This study tested a device that measures hemoglobin and blood flow without needles during surgery. The goal was to see if it helps doctors make better decisions about giving blood transfusions. The study was stopped early and included 43 adults having major surgeries with expecte…

This study explored whether measuring the thickness of a thin layer inside blood vessels (glycocalyx) before heart surgery could predict serious problems like shock, kidney failure, or death. Researchers planned to enroll 130 adults undergoing heart surgery with a heart-lung mach…

This study looked at whether giving patients extra guidance on showering before planned surgery could make their skin cleaner when they arrive at the operating room. It included 22 adults scheduled for various surgeries. The study was stopped early, so results are limited.

This small, terminated study aimed to see if measuring pressure in the esophagus (the tube connecting mouth to stomach) could reliably track when a lung collapses during surgeries that require breathing through only one lung. Researchers planned to compare these pressure readings…