SUBSTANCE-RELATED DISORDERS
Clinical trials for SUBSTANCE-RELATED DISORDERS explained in plain language.
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Mindfulness program shows promise for keeping women in addiction treatment
Disease control CompletedThis study tested a mindfulness-based program designed for low-income women in residential treatment for substance use disorders. The goal was to see if the program could help them stay in treatment longer and reduce the chance of returning to drug or alcohol use. Researchers enr…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated May 26, 2026 11:31 UTC
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New therapy shows promise for teens battling addiction and depression together
Disease control CompletedThis study tested a special therapy (OPT-A) for teens aged 10-17 who have both substance use problems and mood or anxiety disorders. 140 teens took part and were followed for 18 months. The goal was to see if the therapy could reduce drug use and improve mental health better than…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Peer power: new study tests buddy system for opioid recovery
Disease control CompletedThis study tested whether a trained peer recovery specialist could help low-income, minority individuals stick with their medication for opioid use disorder. 200 people in Baltimore took part, comparing the peer-led program to standard care over six months. The goal was to see if…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Maryland, College Park • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Monthly shot vs. daily pills: new hope for opioid treatment in rural america?
Disease control CompletedThis study tested whether a once-monthly injection of buprenorphine works as well as daily pills for people with opioid use disorder living in rural areas. About 140 adults participated, receiving either the injection or daily tablets for 14 weeks. The goal was to see if the mont…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: PHASE3 • Sponsor: Yih-Ing Hser • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Teen driving study tests web tool to curb impaired driving
Prevention CompletedThis study tested a single-session web program called webCHAT aimed at preventing impaired driving among teens. About 200 adolescents aged 15.5 to 17 who were enrolled in driver education took part. The program was designed to reduce driving under the influence of alcohol or cann…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Stanford University • Aim: Prevention
Last updated May 26, 2026 11:34 UTC
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Personality-Targeted program shows promise in preventing teen drug and alcohol abuse
Prevention CompletedThis study tested a school program called Preventure, which aims to prevent alcohol and drug misuse in teenagers by targeting four personality traits linked to substance use. About 3,900 high-risk students from Canadian high schools took part. The program uses group sessions to t…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: St. Justine's Hospital • Aim: Prevention
Last updated May 26, 2026 11:27 UTC
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Personalized craving scale shows promise in addiction treatment
Symptom relief CompletedThis study tested whether adding an individually adjusted therapy scale to standard treatment could reduce craving intensity in people with substance use or behavioral addictions. 151 adults seeking outpatient care participated. The approach aimed to help clinicians tailor treatm…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated May 26, 2026 11:34 UTC
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New workshop helps veterans reclaim civilian life
Symptom relief CompletedThis study tested a workshop called STEP-Home for 221 post-9/11 Veterans who had trouble readjusting to civilian life. The workshop taught practical skills like managing emotions, solving problems, and focusing attention. The goal was to help Veterans feel more connected to their…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 26, 2026 11:24 UTC
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CBD shows promise in easing opioid cravings, brain scans reveal
Symptom relief CompletedThis study looked at how cannabidiol (CBD) affects the brain in people with opioid use disorder who are stable on methadone. Researchers gave 66 participants either CBD or a placebo and used brain scans to measure changes in brain activity related to craving and anxiety. The goal…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: PHASE2 • Sponsor: Yasmin Hurd • Aim: Symptom relief
Last updated May 26, 2026 11:08 UTC
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Step up to sobriety: fitness trackers boost mood in alcohol recovery
Symptom relief CompletedThis study looked at whether using an activity tracker (like a Fitbit) can help people in a hospital program for alcohol use disorder become more active and improve their mood. 90 adults wore the tracker during their treatment. Researchers measured how often they used it, their p…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Oviedo • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Virtual store reveals: would smokers switch if ventilated cigarettes were banned?
Knowledge-focused CompletedThis study looked at what would happen if cigarettes with ventilation holes were banned. 142 smokers used a virtual store to choose between different tobacco products as prices changed. The goal was to see if people would switch to other products like e-cigarettes or nicotine gum…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated May 26, 2026 11:34 UTC
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Peer coaches tested to curb opioid use in Justice-Involved youth
Knowledge-focused CompletedThis pilot study looked at whether paraprofessional coaches (some with personal experience of substance use) can help young adults involved in the justice system reduce their drug use. The study involved 35 participants and measured drug use through urine tests over several month…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Knowledge-focused
Last updated May 26, 2026 11:31 UTC
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AI uncovers hidden subtypes of addiction in new study
Knowledge-focused CompletedThis study used artificial intelligence to analyze personality and behavior data from 155 adults in residential treatment for substance use disorders. The goal was to find hidden patterns that could help doctors tailor treatments to individual patients. No treatment was given; th…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated May 26, 2026 11:29 UTC
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Brain scans reveal hidden effects of opioid use in pregnancy
Knowledge-focused CompletedThis study looked at the brains of 45 pregnant women with opioid use disorder (OUD) who were taking medication therapy, compared to pregnant women without OUD. Researchers used MRI scans to see if OUD and the medication change how different brain regions connect. The goal was to …
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated May 26, 2026 11:22 UTC
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Can a family app help beat the opioid crisis?
Knowledge-focused CompletedThis study tested a digital training program for families (called Concerned Significant Others) to help a loved one with opioid use disorder enter treatment. 45 participants used an online version of the CRAFT method, which teaches communication and support skills. The goal was t…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: We The Village, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 11:08 UTC
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Can a depression scale help in addiction treatment? new study says yes
Knowledge-focused CompletedThis study checked if a questionnaire called the Behavioral Activation for Depression Scale (BADS) works well for people with substance use disorders. Researchers looked at data from 289 adults to see if the scale is reliable and accurate. The goal was to improve how depression i…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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AI could help hospitals identify hidden substance abuse
Knowledge-focused CompletedThis study tested a computer program that scans hospital records to find patients who may be misusing drugs or alcohol. Researchers looked at data from nearly 65,000 adults admitted to the hospital. The goal was to see if the program could help doctors offer counseling and suppor…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC