SARS-COV-2 INFECTION

This study tests two experimental COVID-19 booster vaccines in 80 healthy volunteers aged 40 to 64. The goal is to see if one version, which includes an extra component called 's3', can produce a stronger and longer-lasting immune response. Participants will receive a single shot…

This study tests whether giving the antiviral drug remdesivir for 10 days can prevent severe COVID-19 in kidney transplant patients who have mild or no symptoms. The goal is to safely allow transplants to happen sooner, reducing time on dialysis. About 15 adults will receive remd…

This study tests whether baricitinib, an anti-inflammatory drug, can improve thinking, memory, and physical symptoms like fatigue and shortness of breath in people with Long COVID. About 550 adults who had COVID-19 at least 6 months ago will receive either baricitinib or a placeb…

This early-stage study tests whether special immune cells (T cells) from a donor can prevent COVID-19 in people who recently had a stem cell transplant and have weak immune systems. About 24 adults and children will receive one of three doses of these cells. The main goal is to c…

This study aims to understand why some people, mostly women, develop a fast heart rate and other symptoms like fatigue and brain fog after COVID-19. Researchers will measure immune system activity and nerve function in 60 participants. The goal is to find the cause, not to test a…

This study is creating new ways to test exercise in children with cystic fibrosis, sickle cell disease, or long COVID. Current tests are designed for healthy athletes and don't work well for kids with these conditions. Researchers will track about 240 children over several years …

This study follows 10,000 pregnant women in Nagpur, India, from early pregnancy through 42 days after birth. Researchers want to see if catching flu, COVID-19, or other respiratory viruses raises the risk of problems like preterm labor or severe preeclampsia. The goal is to gathe…

This study looks at why some people with Long COVID develop POTS, a condition causing rapid heartbeat and fatigue when standing. Researchers believe an overactive immune system may be the cause. They are testing a drug called 2-HOBA to see if it can reduce immune markers in 50 ad…