SARS-COV-2 INFECTION

This study tested an extra dose of a new COVID-19 vaccine (PHH-1V) in 241 adults with weakened immune systems, such as those with HIV, kidney disease, or autoimmune disorders. The goal was to see if the booster could improve their protection against the virus and its variants. Re…

This early-stage trial tested a new COVID-19 vaccine given as a nasal spray. The vaccine uses a weakened virus to teach the body to fight SARS-CoV-2. 27 healthy adults aged 18 to 50 took part. The main goals were to check safety and see if the vaccine triggers an immune response.

This study tested updated mRNA vaccines designed to protect against new COVID-19 variants. Over 1,000 healthy people aged 12 and older received a single dose. Researchers monitored side effects and measured immune responses to see how well the vaccines worked.

This large study tested the safety and effectiveness of the Pfizer-BioNTech COVID-19 vaccine in nearly 47,000 healthy volunteers aged 12 and older. Participants received two doses of the vaccine or a placebo, and researchers tracked how many got COVID-19. The vaccine proved highl…

This study tested whether giving a combined COVID-19 and flu vaccine as one shot is safe and helps the body build defenses against both viruses. It involved 644 healthy adults aged 50 and older. Researchers measured side effects and antibody levels to see how well the combo worke…

This study tested several updated COVID-19 booster vaccines in over 1,400 healthy people aged 12 and older who had already received prior COVID-19 vaccines. The goal was to see if these new boosters were safe and could improve the body's immune response against newer virus varian…

This large study tested whether giving extra doses (boosters) of the Pfizer-BioNTech COVID-19 vaccine to healthy people who already had the vaccine is safe and helps prevent COVID-19. Over 16,000 people took part, and the study looked at different booster schedules and doses. The…

This study tested three new self-amplifying RNA vaccines against COVID-19 in 72 healthy adults, including some who had already been vaccinated and some who had not. The main goals were to check safety and measure the immune response. The vaccines were designed to help the body fi…

This study tested how well two different 2023-2024 updated COVID-19 vaccines (Novavax and Pfizer mRNA) protect adults from getting sick with COVID-19. About 1,188 adults who had already received at least two mRNA vaccine doses took part. Some got the Novavax vaccine, some got the…

This early-stage study tested a new COVID-19 vaccine called ABNCoV2 in 45 healthy adults who had never had COVID-19. The goal was to check the vaccine's safety and see how well it triggers an immune response. Researchers gave two doses, with or without an immune booster (adjuvant…

This study tested the safety and immune response of different COVID-19 booster vaccines in about 1,900 adolescents and adults aged 12 to 64 in Kenya, Democratic Republic of Congo, and Rwanda. It included people with and without HIV to see how well the vaccines work in these group…

This study tested a single dose of a new COVID-19 vaccine (AVX/COVID-12) in 158 healthy adults who already had some immunity to the virus. The vaccine was given either as a shot or a nasal spray to see which route works better and is safe. Researchers measured antibody and T-cell…

This study tested the Moderna COVID-19 mRNA vaccine in over 14,000 people living with HIV or other conditions that raise the risk of severe COVID-19. Researchers compared different vaccine schedules to see which best prevents COVID-19. The goal was to find the most effective way …

This early-stage study tested a new RNA-based COVID-19 booster vaccine (BNT162b4) in 383 healthy adults who had already received a COVID-19 vaccine. The goal was to find a safe dose and see how well the vaccine boosts the immune system. Participants received either the new vaccin…

This study tested whether BIMERVAX, a COVID-19 booster shot, is safe and works well in teenagers aged 12 to 17. About 242 teens who had already received a different COVID vaccine got one dose of BIMERVAX. Researchers measured their immune response and tracked any side effects for…

This study tested a new booster vaccine for COVID-19 in over 4000 healthy adults who had already been vaccinated. The goal was to see if the new booster works as well as a current vaccine and is safe. Participants received one shot and were monitored for immune response and side …

This study tested three different batches of the Novavax COVID-19 vaccine to make sure they all work the same. About 900 adults aged 18 to 49 who had already been vaccinated took part. Researchers measured their immune response and checked for safety issues.

This study checked how safe and effective the COVID-19 medicine PAXLOVID is in real-world use. Over 3,300 people aged 12 and older who took PAXLOVID were watched for 28 days. Researchers tracked side effects and whether the infection got worse. The goal was to see how well the me…

This study tested a new, fast, and affordable COVID-19 test called TestNPass. It uses a nose swab to detect the virus and aims to be as accurate as possible. The study involved 400 adults at a hospital in France. The goal was to see if TestNPass can reliably diagnose SARS-CoV-2 i…

This study tested new portable sensor platforms to quickly and cheaply detect viruses (like SARS-CoV-2), bacteria, and parasites in blood and respiratory samples. Researchers compared the sensors' accuracy to standard lab tests using samples from 149 adult patients. The goal is t…

This study looked at whether testing saliva (spit) is as good as the standard nose swab for finding COVID-19. Over 5,000 people provided both a nose swab and a saliva sample. The goal was to see if saliva testing could make screening easier and more comfortable while still being …

This study looked at whether two drugs, hydroxychloroquine and azithromycin, could prevent hospital workers from catching COVID-19. About 122 workers without signs of infection took one of the drugs or a placebo for 40 days. The goal was to see if fewer people got infected compar…

This study looked at whether taking moderate (4,000 IU) or high (10,000 IU) doses of vitamin D daily could lower the risk of getting COVID-19 compared to a low dose (400 IU). About 1,475 adults from the Chicago area took part for 9 months. Researchers tracked who got a confirmed …

This study looked at whether the antiviral drug remdesivir can reduce symptoms of Long COVID. 73 adults with confirmed Long COVID received the drug for five days and were monitored for about 8 weeks. The main goal was to see if this treatment approach is practical and tolerable f…

This study tested an experimental antiviral pill called S-217622 in over 2,000 adults with mild to moderate COVID-19 who were not hospitalized. Participants started the pill within 3 days of symptoms. The goal was to see if the pill could shorten symptom duration and lower virus …

This study followed over 1,000 people in the Dominican Republic to learn how COVID-19 spreads and how to control it. Researchers tracked symptoms, tested blood for antibodies, and asked about handwashing habits. The goal was to understand the virus better and find ways to reduce …

This study looked at placentas and umbilical cord blood from 68 women who had COVID-19 during pregnancy. Researchers checked for changes in the placenta's structure, genes, and signs of inflammation to see if the infection affected the baby's health. The goal was to learn more ab…

This study tracked 366 people in Japan who received Evusheld to treat or prevent COVID-19. The goal was to see what side effects occurred in real-world use. The study focused on serious allergic reactions and heart problems. Results help doctors understand the drug's safety profi…

This completed Phase 2 trial tested the safety and effectiveness of different drug combinations in people with COVID-19. It used a master protocol that allowed both hospitalized and non-hospitalized patients to join. Only 4 participants were enrolled, and the study focused on mea…

This study checked the immune status of 1,024 police officers in Bern, Switzerland, against COVID-19 over one year. Researchers looked at how work and home life affected infection risk and how often protective gear was used. The goal was to learn more about virus spread in this g…

This early study tested a new PET/CT imaging agent in 5 adults who had recovered from COVID-19. The goal was to see if the tracer could detect lung damage caused by the virus. Participants had no prior lung disease and needed two negative COVID tests before each scan. The study w…

This study gave healthy volunteers aged 18 to 40 a carefully measured dose of the Omicron BA.5 virus to see how many got infected and how their bodies reacted. The goal was not to treat or cure COVID-19, but to learn about the virus's behavior and safety in a controlled setting. …

This completed study collected biological data from 249 adults with SARS-CoV-2 or influenza infections. Researchers used a systems biology approach to analyze the complex factors that cause different symptoms in different people. The goal was to identify key biological markers th…

This study looked at how the COVID-19 pandemic affected the health of people aged 75 and older and their caregivers. Researchers analyzed medical records and interviewed participants to understand changes in health, daily routines, and care needs. The goal is to find ways to impr…

This study collected blood, urine, and kidney tissue samples from 90 hospitalized COVID-19 patients who also had acute kidney injury. Researchers aimed to better understand how COVID-19 affects the kidneys and to identify potential treatments. Participants were followed up three …

This study checked if leftover COVID-19 virus in the nose is linked to ongoing brain fog and memory problems. Researchers compared 51 adults who had COVID-19 months earlier—some with brain fog, some without. They looked for virus in the nasal cavity and matched it to thinking dif…