New COVID boosters tested in thousands – could they beat new variants?

NCT ID NCT05472038

Completed ⭐️ VACCINE ⭐️ Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 42 times

Summary

This study tested several updated COVID-19 booster vaccines in over 1,400 healthy people aged 12 and older who had already received prior COVID-19 vaccines. The goal was to see if these new boosters were safe and could improve the body's immune response against newer virus variants. Participants received a single shot and were followed for about 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Accellacare - Charlotte

Charlotte, North Carolina, 28211, United States
Accellacare - Wilmington

Wilmington, North Carolina, 28401, United States
Acevedo Clinical Research Associates

Miami, Florida, 33142, United States
Anaheim Clinical Trials, LLC

Anaheim, California, 92801, United States
Bayview Research Group, LLC

Valley Village, California, 91607, United States
Benchmark Research

Austin, Texas, 78705, United States
California Research Foundation

San Diego, California, 92123, United States
Centricity Research Columbus Ohio Multispecialty

Columbus, Ohio, 43213, United States
Clinical Neuroscience Solutions Inc.

Memphis, Tennessee, 38119, United States
Clinical Neuroscience Solutions, Inc. dba CNS Healthcare

Jacksonville, Florida, 32256, United States
Clinical Research Atlanta

Stockbridge, Georgia, 30281, United States
Clinical Research Consulting

Milford, Connecticut, 06460, United States
Clinical Research Professionals

Chesterfield, Missouri, 63005, United States
DM Clinical Research - Bellaire

Houston, Texas, 77081, United States
DM Clinical Research - MDC

Tomball, Texas, 77375, United States
Diablo Clinical Research, Inc.

Walnut Creek, California, 94598, United States
East-West Medical Research Institute

Honolulu, Hawaii, 96814, United States
IMA Clinical Research San Antonio

San Antonio, Texas, 78229, United States
J. Lewis Research, Inc. / Foothill Family Clinic

Salt Lake City, Utah, 84109, United States
J. Lewis Research, Inc. / Foothill Family Clinic South

Salt Lake City, Utah, 84121, United States
Kaiser Permanente Northwest Center for Health Research

Portland, Oregon, 97227, United States
Kentucky Pediatric/ Adult Research

Bardstown, Kentucky, 40004, United States
PharmQuest Life Sciences, LLC

Greensboro, North Carolina, 27408, United States
Research Centers of America ( Hollywood )

Hollywood, Florida, 33024, United States
Rochester Clinical Research, LLC

Rochester, New York, 14609, United States
Senders Pediatrics

Cleveland, Ohio, 44121, United States
South Jersey Infectious Disease

Somers Point, New Jersey, 08244, United States
Sundance Clinical Research

St Louis, Missouri, 63141, United States
Tekton Research, LLC.

Austin, Texas, 78745, United States
Velocity Clinical Research, Omaha

Omaha, Nebraska, 68134, United States
Virginia Research Center

Midlothian, Virginia, 23114, United States

Conditions

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COVID-19 SARS-COV-2 INFECTION