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New booster shot shows promise for protecting vulnerable patients against COVID-19

NCT ID NCT05303402

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tested an extra dose of a new COVID-19 vaccine (PHH-1V) in 241 adults with weakened immune systems, such as those with HIV, kidney disease, or autoimmune disorders. The goal was to see if the booster could improve their protection against the virus and its variants. Researchers measured antibody levels before and after the shot to check immune response and safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ankara University Medical Faculty Hospitals

    Ankara, Ankara, 06620, Turkey (Türkiye)

  • Hacettepe University Medical Faculty Hospitals

    Ankara, Ankara, 06230, Turkey (Türkiye)

  • Hospital Clínic de Barcelona

    Barcelona, Barcelona, 08036, Spain

  • Hospital Germans Trias i Pujol

    Badalona, Barcelona, 08916, Spain

  • Hospital Josep Trueta

    Girona, Girona, 17001, Spain

  • Koc University Hospital

    Istanbul, Istanbul, 34010, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.