PULMONARY HYPERTENSION

This study tested a device called the Atrial Flow Regulator in 32 people with severe pulmonary hypertension, a condition where blood pressure in the lungs is dangerously high. The device creates a small, controlled hole in the heart to relieve pressure. The main goal was to see i…

This study tested a procedure called pulmonary artery denervation (PADN) in 30 adults with both heart failure and high blood pressure in the lungs. Participants had already been on standard heart failure medications for at least a month. The goal was to see if PADN could safely i…

This study tested a single infusion of stem cells from donated umbilical cord tissue in people with severe scleroderma that also affects the lungs. The goal was to see if the treatment could improve lung function, exercise ability, and quality of life. Only one person took part, …

This study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …

This study looked at 52 adults having heart valve surgery who also had high blood pressure in their lungs. Doctors gave one group a drug called levosimendan and the other group dobutamine to see which one better helped the right side of the heart work after surgery. The team chec…

This study checked the long-term safety of an inhaled powder drug (treprostinil palmitil) in 31 people with pulmonary hypertension caused by interstitial lung disease. Participants had already completed a previous study of the same drug. The main goal was to see how many had side…

This study looked at how 16 people with pulmonary hypertension (PH) responded to a single session of active video games compared to a traditional home exercise session. Researchers measured heart rate, blood pressure, shortness of breath, and how much participants enjoyed each ac…

This study tested a special education program for 49 adults with pulmonary hypertension, a chronic lung disease causing shortness of breath and fatigue. The program included face-to-face lessons, videos, and regular phone check-ins over nine months to help patients manage symptom…

This study looked at whether a 10-week aerobic exercise program can help people with pulmonary hypertension (high blood pressure in the lungs) walk farther and feel better. About 97 adults aged 21 to 82 took part, with some starting exercise right away and others waiting 10 weeks…

This study tested whether an Apple Watch can reliably measure key health indicators like oxygen use during exercise in people with heart conditions. Researchers compared smartwatch data to standard medical equipment in 50 adults with heart disease or in athletes. The goal was to …

This study tested whether a special MRI scan (4D flow MRI) can accurately measure blood pressure in the lungs without needing a heart catheter. 28 adults with pulmonary hypertension had both the MRI and the standard catheter test, plus an ultrasound. The goal was to see if the MR…

This study looked at how well different heart pressure tests work. Researchers compared non-invasive ultrasound (echocardiography) with invasive catheter measurements in 623 adults. The goal was to see which tests best detect high pressure in the heart's main chamber, a key sign …

This study looked at nearly 1,000 adults with sickle cell anemia to find out how many also develop pulmonary hypertension (high blood pressure in the lungs). Participants had heart ultrasounds and blood tests, then were followed by phone for up to 3 years. The goal was to learn h…

This study looked at medical records of 59 adults with COPD to see if a standard breathing and exercise program (pulmonary rehabilitation) works as well for those who also have pulmonary hypertension (high blood pressure in the lungs). Researchers compared how far people could wa…

This study checked if the Londrina Daily Living Activities Protocol is a valid and reliable tool for people with pulmonary hypertension. Forty adults completed tasks like walking and organizing objects while their oxygen use and time were measured. The goal was to see if this tes…