New MRI scan could replace risky heart catheterization for lung pressure diagnosis
NCT ID NCT05103189
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special MRI technique called 4D flow can accurately measure blood pressure in the lungs of people with pulmonary hypertension. 28 patients had both the MRI and the standard invasive catheterization to compare results. If the MRI proves reliable, it could offer a safer, needle-free way to diagnose and monitor this serious condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 4D flow MRI sequence
- What this could lead to
- If successful, this could provide a non-invasive, radiation-free way to diagnose and monitor pulmonary hypertension, reducing the need for risky heart catheterization.
- What could go wrong
- This is a small, completed study with only 28 participants. The technique may not be accurate enough to replace catheterization in all patients, and more research is needed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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28 people
The number who actually took part.
- Started
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Oct 2021
- Finished
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Jul 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years old, * Patient referred for cardiac MRI who previously underwent right heart catheterization for pulmonary hypertension assessment, * Affiliation to a social security program, * Ability of the subject to understand and express opposition Exclusion Criteria: * Age \<18 years old, * Major obesity (\> 140 kg) not allowing the patient to enter the tunnel of the machine whose diameter is less than 70 cm, * Person under guardianship or curators, * Pregnant woman, * Allergy to gadolinium chelates, * Claustrophobia, * Any contraindications to MRI
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens-Picardie
Amiens, 80000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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