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Heart study reveals best ways to measure hidden pressure

NCT ID NCT07512310

Knowledge-focused Sponsor: University Hospital, Essen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 623 adults with heart failure or high blood pressure in the lungs to see how well different tests measure pressure inside the heart. Doctors used both non-invasive ultrasound (echocardiogram) and invasive catheter measurements to check for elevated filling pressure, which can cause shortness of breath. The goal was to understand which methods work best to guide treatment decisions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

623 people

The number who actually took part.

Started

Mar 2018

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Consecutive adult patients undergoing clinically indicated left- and right-heart catheterisation at the West German Heart and Vascular Centre Essen, University Hospital Essen, Germany, with available invasive haemodynamic measurements and echocardiographic assessment as part of routine clinical care.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥18 years) * Clinically indicated left- and right-heart catheterisation under resting conditions * Availability of invasive left ventricular end-diastolic pressure (LVEDP) measurement * Availability of pulmonary capillary wedge pressure (PCWP) measurement * Availability of transthoracic echocardiography within 5 days of cardiac catheterisation * Adequate echocardiographic image quality for analysis Exclusion Criteria: * Missing or incomplete invasive haemodynamic measurements (LVEDP or PCWP) * Missing or non-interpretable echocardiographic data * Haemodynamic instability at the time of measurement * Incomplete data required for analysis

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Conditions

The condition(s) this trial relates to.

cardiac ventricle disorder heart failure left ventricular failure pulmonary hypertension Ventricular Dysfunction Ventricular Dysfunction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure Pulmonary hypertension Ventricular dysfunction Ventricular dysfunction, left

Contacts and locations

Locations

  • West German Heart and Vascular Centre Essen, University Hospital Essen

    Essen, Essen, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.