PULMONARY DISEASE

This study tests whether having extra appointments with a heart specialist at a local GP practice helps people at high risk get better treatment for heart, kidney, metabolic, and lung conditions. About 138 adults from a previous study (FIND-AF) will either receive these specialis…

This study tests a new device combination (Alterra Prestent and SAPIEN 3 valve) to repair a leaky pulmonary heart valve in people born with heart defects. About 86 participants with moderate or severe leakage will get the device through a tube in a blood vessel, avoiding open-hea…

This study looks at whether noninvasive biomarkers (like those found in breath or blood) can accurately tell if a lung nodule is cancerous or benign in high-risk smokers. Researchers will follow 85 participants with lung nodules to validate these biomarkers alongside standard ima…

This study tests if adding a freezing spray (cryospray) to standard treatments can keep narrowed airways open longer in people with benign airway stenosis. About 40 adults with significant airway narrowing will be randomly assigned to get either standard care alone or standard ca…

This study was designed to test if a non-invasive blood pressure monitor could measure how well the heart is pumping in people with a pulmonary embolism (a blood clot in the lungs). The goal was to see if these measurements could help doctors predict which patients are at risk of…

This study looks for early warning signs of lung cancer in people at high risk, such as smokers aged 50-79 with COPD or a family history of lung cancer. Researchers will test blood and breath samples to find biomarkers that could predict lung cancer before symptoms appear. The go…

This study uses advanced heart scans (coronary CT angiography) to understand why people with rheumatoid arthritis face higher risks of heart disease, lung problems, and depression. Researchers will follow 4,000 participants aged 50-75 for up to 10 years, collecting blood samples,…

This study was designed to test a new 'leak-free' adapter for bronchoscopy in patients on breathing machines. The goal was to see if it could reduce air loss and aerosol spread into the operating room. However, the study was withdrawn before any participants were enrolled.