Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New study aims to catch lung cancer before symptoms start

NCT ID NCT02504697

Knowledge-focused Sponsor: Boston University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking for early signs of lung cancer in people at high risk, such as older smokers or those with COPD. Researchers will collect blood and airway samples from 665 participants to find biomarkers that could predict lung cancer before symptoms appear. The goal is to improve screening so that lung cancer can be caught earlier, when treatment is more likely to work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple test that spots lung cancer earlier, when it's easier to treat, and helps focus screening on those at highest risk.
What could go wrong
This is an observational study, not a treatment trial. The biomarkers found may not prove accurate enough for widespread use, and results may take years to confirm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

665 people

The number who actually took part.

Started

Sep 2011

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Military personnel

Ages

50 to 79 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for longitudinal screening cohort * Ages 50 to 79 years; * Smoking status: Current or former smoker (≥10 cigarettes/day for current smokers, or ≥20 pack years for former smoker who quit 20 years ago or less) * History of Chronic Obstructive Pulmonary Disease (COPD), emphysema, or at least one first-degree relative with a diagnosis of lung cancer; * Willing to undergo fiberoptic bronchoscopy; * Able to tolerate all biospecimen collection as required by protocol; * Able to comply with standard-of-care follow-up visits, including clinical exams, diagnostic work-ups, and imaging for a maximum of four years or until diagnosis of lung cancer; * Able to fill out Patient Lung History questionnaire; * Willing and able to provide a written informed consent. Exclusion Criteria * Diagnosis of lung cancer prior to the current assessment (that is, patients are eligible if first lung cancer diagnosis has been recently confirmed by bronchoscopic biopsy and is leading to resection surgery, but not if this is not a first diagnosis); * Contraindications to nasal brushing or fiberoptic bronchoscopy, including: ulcerative nasal disease, hemodynamic instability, severe obstructive airway disease (i.e., disease severity does not allow for bronchoscopic procedures), unstable cardiac or pulmonary disease, as well as other comorbidities leading to inability to protect airway, or altered level of consciousness; * Allergies to any local anesthetic that may be used to obtain biosamples in the study; * Weight greater than that allowable by the CT scanner.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chronic obstructive pulmonary disease are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease lung cancer lung disorder pulmonary emphysema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pulmonary disease

Contacts and locations

Locations

  • Boston University Medical Center

    Boston, Massachusetts, 02118, United States

  • Boston VA Research Institute, Inc

    Boston, Massachusetts, 02132, United States

  • Dallas VA Research Corporation

    Dallas, Texas, 75216, United States

  • Denver Research Institute

    Denver, Colorado, 80220, United States

  • Health Research Inc. Roswell Park Division

    Buffalo, New York, 14263, United States

  • Middle Tennessee Research Institute (Vanderbilt University)

    Nashville, Tennessee, 37212, United States

  • Naval Medical Center Portsmouth

    Portsmouth, Virginia, 23708, United States

  • Naval Medical Center San Diego

    San Diego, California, 92134, United States

  • Regents of the University of California LA (Los Angeles VA Healthcare System)

    Los Angeles, California, 90073, United States

  • San Antonio Military Medical Center

    San Antonio, Texas, 78219, United States

  • Trustees of University of Pennsylvania (Philadelphia VA Medical Center)

    Philadelphia, Pennsylvania, 19104, United States

  • University of California Los Angeles Medical Center

    Los Angeles, California, 90095, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Veterans Research Foundation of Pittsburgh

    Pittsburgh, Pennsylvania, 14520, United States

  • Walter Reed National Military Medical Center

    Bethesda, Maryland, 20889, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.