Boston University

This study tests a 5-session virtual program called MATTER for 256 people living with HIV and substance use disorders in Boston and Miami. The program uses text messages and coaching to help people manage stigma and shame, set self-care goals, and build self-compassion. The goal …

This study tests whether a combination cream (5-fluorouracil plus calcipotriene) applied for just 7-14 days can clear two types of low-risk skin cancer as effectively as the standard 4-week treatment. About 200 adults with superficial basal cell carcinoma or squamous cell carcino…

This study aims to help people with HIV stay in care, especially during the first six months after starting or restarting treatment—a time when many drop out. Researchers are creating a toolkit that includes a risk assessment, a menu of support options, a treatment roadmap, and a…

This study tests two short counseling programs for veterans who have experienced intimate partner violence (IPV) in the past year. One program offers up to 8 sessions focused on strengths and empowerment, while the other is a single session with safety planning and resources. Res…

This study tests different types and doses of vitamin K in people aged 60 and older with knee osteoarthritis. The goal is to see if vitamin K can improve markers related to joint health. Participants will take vitamin K pills and have blood tests over the study period.

This study tests a stress management program called Vietnamese Self Help Plus (vSH+) for women with breast or gynecologic cancer in Vietnam. About 285 participants will either receive the program or standard care. The goal is to see if the program reduces anxiety and depression a…

This study tests whether adding memory-support techniques to standard PTSD therapy helps people learn and remember key therapy content. About 100 adults with PTSD will receive either standard therapy or therapy with extra memory aids. The goal is to see if better recall leads to …

This study tests whether adding a brief writing exercise called AWARE to standard PTSD therapies (CPT or PE) can improve communication between patients and therapists and lead to better outcomes. About 54 adults with PTSD will participate, first in a small pilot phase and then in…

This study looks at three ways to manage pain in young children after dental surgery done under general anesthesia. The three options are ibuprofen alone, ibuprofen and acetaminophen given at different times, or both given together. The goal is to find which method works best to …

This study tests whether wearing virtual reality (VR) glasses during oral surgery can lower anxiety and reduce the amount of sedation medicine needed. About 80 adults having non-emergency oral surgery will be randomly assigned to either watch a relaxing VR video or wear plain pro…

This study tests a new 3D-printed device that guides numbing injections for dental procedures. The goal is to make the injection more accurate, reduce pain, and lower the chance of it not working. Ten adults needing a root canal on a lower tooth will try the device, and researche…

This study tests a new, painless imaging method called spatial frequency domain imaging (SFDI) to measure skin thickness in people with scleroderma. Currently, doctors use a subjective 'pinch test' that can vary between doctors. The study will compare SFDI to the pinch test and u…

This study reviews medical records from up to 1 million people in Malawi to understand how HIV treatment services are provided. Researchers want to see which care models work best, how many patients use them, and what they cost. No new treatments are tested—the goal is to gather …

This study follows 150 adults with advanced HIV who are hospitalized in South Africa. Researchers will interview them in the hospital and again 4 and 8 weeks after discharge to see if they return to their local clinic for ongoing HIV treatment. The goal is to find where the care …

This study tests whether a telehealth interview before a dental checkup helps youth with intellectual or developmental disabilities (IDD) and their dentists. About 50 participants will be randomly assigned to have a video call or not. Researchers will measure if the video group m…

This study from Boston University is checking how accurately wrist-worn devices (like smartwatches) measure exercise intensity. Fifty-four adults will wear these devices while doing different activities, and researchers will compare the device data to a precise lab measurement. T…

This study follows 10,000 pregnant women in Nagpur, India, from early pregnancy through 42 days after birth. Researchers want to see if catching flu, COVID-19, or other respiratory viruses raises the risk of problems like preterm labor or severe preeclampsia. The goal is to gathe…

This study looks at medical records from millions of people with HIV in South Africa to understand how different ways of delivering HIV care are working. Researchers want to see how many people are using these models, how well they control the virus, and what the costs are. No ne…

This study looks at medical records from over a million people in Zambia to see how different ways of delivering HIV care are working. The goal is to understand which models help more patients stay on treatment and achieve viral suppression. No new treatments are being tested; in…

This study looks at how changes in the way your teeth come together (your bite) might affect your balance and walking. Researchers will use dental splints or dentures to temporarily change the bite height in healthy adults aged 30-45 and denture wearers aged 50-65. They will meas…