PULMONARY ARTERIAL HYPERTENSION
Clinical trials for PULMONARY ARTERIAL HYPERTENSION explained in plain language.
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New drug targets root cause of deadly lung pressure disease
Disease control Not yet recruitingThis study is testing whether a compound called 2-HOBA can help control pulmonary arterial hypertension, a serious condition where high blood pressure in the lungs strains the heart. Researchers will give 2-HOBA to 12 adult patients already on standard medications to see if it im…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Doctors review Real-World results when switching a key drug for serious lung condition
Disease control Not yet recruitingThis study looks back at the medical records of 15 adults with pulmonary arterial hypertension, a serious lung and heart condition. The patients were already on a standard three-drug combination but switched one specific medication (a phosphodiesterase-5 inhibitor) to a different…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Sponsor: Caio Júlio César dos Santos Fernandes • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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New hope for PAH patients: daily inhaler aims to boost stamina
Disease control Not yet recruitingThis study aims to see if a new once-daily inhaled powder can help adults with pulmonary arterial hypertension (PAH) walk farther and feel better. It will compare the new treatment to a placebo (inactive powder) over 24 weeks in about 344 people who are already on stable PAH medi…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Phase: PHASE3 • Sponsor: Insmed Incorporated • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New pill could help people with rare Lung-Heart disease breathe easier
Disease control Not yet recruitingThis study is testing a new oral medication called NS-863 for adults with pulmonary arterial hypertension (PAH), a serious condition where high blood pressure in the lungs strains the heart. Researchers will compare three different doses of NS-863 against a placebo (inactive pill…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Phase: PHASE2 • Sponsor: NS Pharma, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Major trial tests new hope for deadly lung pressure disease
Disease control Not yet recruitingThis Phase 3 study is testing whether the experimental drug IKT-001 can help adults with pulmonary arterial hypertension, a serious condition where blood pressure in the lungs is dangerously high. Researchers will measure if the drug reduces pressure in the lung's blood vessels a…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Phase: PHASE3 • Sponsor: Inhibikase Therapeutics • Aim: Disease control
Last updated Mar 09, 2026 14:22 UTC
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Can home workouts ease the burden of a serious lung and heart condition?
Symptom relief Not yet recruitingThis study is testing if a 12-week, home-based exercise program can help people newly diagnosed with pulmonary arterial hypertension feel better and walk farther. Researchers will compare 40 patients who start the program early to those who wait, measuring walking distance, quali…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Phase: NA • Sponsor: Golden Jubilee National Hospital • Aim: Symptom relief
Last updated Mar 11, 2026 14:53 UTC
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Mountain pregnancy mystery: why thin air causes complications?
Knowledge-focused Not yet recruitingThis study aims to understand how living at high altitude affects pregnant women's hearts and their babies' growth. Researchers will follow 20 women in Bolivia living above 3,500 meters, comparing healthy pregnancies with those having complications like high blood pressure. They'…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Scientists probe nighttime breathing and heart rhythms to predict risks in serious lung condition
Knowledge-focused Not yet recruitingThis study aims to better understand how nighttime breathing problems and related changes in heart rate patterns affect people with pulmonary hypertension, a serious condition of high blood pressure in the lungs. Researchers will monitor 60 patients over two years using sleep stu…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC