PREVENTION

This study tests whether adding a drug called aprepitant to standard anti-nausea treatments can better prevent vomiting and nausea after surgery. It involves 260 adults at high risk for these symptoms who are having outpatient surgery. The goal is to see if the combination keeps …

This study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (bladder bleeding) in people who have received a stem cell transplant for blood cancers or severe aplastic anemia. About 266 participants will be randomly …

This study tests a program called REMINDER4Care, designed to help older adults (65+) living in residential or daycare facilities reduce their risk of dementia. The program focuses on social activities, mental exercises, and other healthy lifestyle changes. Researchers will compar…

This study tests whether a daily probiotic drink containing Lacticaseibacillus rhamnosus can reduce or prevent common colds and flu in healthy children aged 3 to 12. Over 12 weeks of treatment and 16 weeks of follow-up, researchers will compare infection rates between the probiot…

This study tests whether a virtual assistant (a chatbot) can help older adults stay on track with a home exercise program. Seventy people aged 60 and older will either use the chatbot for 12 weeks or join a standard in-person class. The main goal is to see if the chatbot group co…

This study is creating an educational tool to help women and their doctors make informed choices about using a hormone-releasing IUD to prevent endometrial cancer. The tool will be tested with 270 women who are at risk or have had the disease. The goal is to make prevention optio…

This study tests whether using repeat CT scans of the heart to track plaque buildup can improve cholesterol control and prevent major heart problems like heart attacks and strokes. About 3,100 adults with non-obstructive coronary artery disease will be randomly assigned to either…

This study tests if Dialectical Behavioral Therapy (DBT), which teaches mindfulness and coping skills, can help teens aged 14-17 with obesity and mild depression improve their quality of life and manage weight to prevent type 2 diabetes. Participants are randomly assigned to life…

This study aims to increase colorectal cancer screening among African Americans, who face higher rates of this cancer. Researchers will provide 1,200 participants aged 45-75 with free take-home test kits and educational materials. Some participants will also see social media ads …

This study compares two ways of giving the drug ondansetron (a lozenge that dissolves in the mouth versus an injection into a vein) to prevent shivering in women having a cesarean section. About 90 women will take part. The goal is to see which method works better at stopping shi…

This study tests whether taking short, 5-minute exercise breaks at work can prevent muscle and joint pain in workers. 150 active workers aged 18 and older will be split into two groups: one doing strength exercises and the other doing stretching exercises. They will do these brea…

This study tests whether alpha lipoic acid, a common antioxidant supplement, can prevent or reduce skin irritation caused by radiation therapy in breast cancer patients. Forty women scheduled for radiation will take the supplement and be monitored for skin reactions and inflammat…

This study tests whether an AI-powered chatbot can help African American adults learn more about oral cancer and its prevention compared to traditional educational handouts. About 60 participants will be split into two groups, and their knowledge will be measured before and after…

This study is testing if data from a smart ring, smartwatch, and smartphone app can help identify people with prediabetes. Researchers will track 200 adults aged 45 and older who are overweight but don't have diabetes. Participants wear the devices for about 4 weeks and log their…

This study looks at whether carbon fiber insoles can help healthy, active men jump higher and sprint faster. About 38 men aged 18-30 will do jump and sprint tests with and without the insoles. The goal is to measure any performance changes, not to treat or cure any disease.